Results 241 to 250 of about 348,393 (352)

Homoharringtonine suppresses acute myeloid leukemia progression by orchestrating EWSR1 phase separation in an m6A‐YTHDF2‐dependent mechanism

open access: yesiMeta, EarlyView.
Homoharringtonine (HHT), a clinically approved anti‐leukemic drug, directly binds the RNA‐binding protein EWSR1. HHT induces an allosteric conformational switch in the RNA recognition motif of EWSR1, driving self‐association and liquid–liquid phase separation (LLPS). The resulting condensates act as regulatory hubs that sequester the m6A reader YTHDF2,
Ting‐Ting Liu   +17 more
wiley   +1 more source

Antimicrobial Susceptibility Determination of Less Frequently Isolated <i>Legionella</i> Species by Broth and Agar Dilution. [PDF]

open access: yesAntibiotics (Basel)
Farley C   +9 more
europepmc   +1 more source

Antimicrobial effect of colloidal argentum colloid on ampicillin resistant Staphylococcus aureus [PDF]

open access: green, 2019
Suhaib Ul Haq Khan   +7 more
openalex  

The interplay between tissue‐resident microbiome and host proteins by integrated multi‐omics during progression of colorectal adenoma to carcinoma

open access: yesiMeta, EarlyView.
This study integrated metagenomic and proteomic profiling of 185 colorectal tissue samples—spanning adenoma (A), tumor (T), and para‐tumor (P)—to characterize multi‐kingdom microbiome and host protein dynamics in colorectal cancer (CRC). In total, 4057 bacterial, 61 fungal, 108 archaeal, and 374 viral species were identified, revealing CRC‐specific ...
Di Wu   +22 more
wiley   +1 more source

Case report: Ampicillin-induced stone formation causing bilateral ureteral obstruction during pelvic surgery

open access: gold, 2019
Athena Christakos   +4 more
openalex   +1 more source

Mortality after broad‐ versus narrow‐spectrum antibiotic treatment for patients with nursing and healthcare‐associated pneumonia: A nationwide retrospective cohort study

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. The effectiveness of broad‐spectrum antibiotics in treating NHCAP remains unclear.
Jumpei Taniguchi   +4 more
wiley   +1 more source

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