Results 261 to 270 of about 228,730 (331)

Effect of metformin on airway inflammation in obese asthmatic mice and study of the mechanism involved. [PDF]

Sci Rep
Xing Y, Shu Z, Lei J, Zheng X, Hou G, Li W, Wang Z, Zhao L.   +7 more
europepmc   +1 more source

Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer

Nature, 2018
Di Wu, Di Hu, Hao Chen, G. Shi, I. Fetahu, Feizhen Wu, Kimberlie Rabidou, Rui Fang, Li Tan, Shuyun Xu, Hang Liu, C. Argueta, Lei Zhang, Fei Mao, Guo-quan Yan, Jiajia Chen, Zhao-Ru Dong, Ruitu Lv, Yufei Xu, Mei Wang, Yong Ye, Shike Zhang, D. Duquette, S. Geng, Clark Yin, C. Lian, G. Murphy, G. Adler, R. Garg, L. Lynch, Pengyuan Yang, Yiming Li, F. Lan, Jia Fan, Yang Shi, Y. Shi   +35 more
semanticscholar   +1 more source

AMPK goes interactive [PDF]

Nature Reviews Molecular Cell Biology, 2007
openaire   +1 more source

T‐Cell Immunity and Lung Cancer

Respirology, EarlyView.
ABSTRACT Lung cancer remains a leading cause of cancer mortality worldwide. Although immune checkpoint inhibitors (ICIs) have reshaped therapeutic strategies in lung cancer, their benefits remain limited. ICIs exert their therapeutic efficacy by activating T‐cell effector functions, underscoring the central role of T cells in antitumor immunity.
Kotaro Yamada, Yosuke Togashi
wiley   +1 more source

D-limonene modulates AMPK signaling to inhibit ox-LDL-induced foam cell formation. [PDF]

Sci Rep
Luo G, Fang F, Guo Y, Li Y, Luo X.
europepmc   +1 more source

Pathogenesis of Age‐Related Hearing Loss and Therapeutic Strategies

Sensory Neuroscience, EarlyView.
ABSTRACT Age‐related hearing loss (ARHL) is a degenerative disorder of the auditory system, characterized by bilateral symmetrical sensorineural hearing loss that occurs with aging. As a highly prevalent age‐related condition worldwide, ARHL significantly impairs both the quality of life and mental health of the elderly.
Yu Xiao, Jiaxin Liu, Xiaohan Zhang, Miao Chang, Cheng Cheng, Yunhao Wu, Xiaolong Fu   +6 more
wiley   +1 more source

Hepatic-vascular crosstalk via GRK2: fenofibrate improves endothelial function by restoring lipid metabolism and NO signaling in obese mice. [PDF]

Front Physiol
Taguchi K, Yonaiyama H, Furukawa T, Matsumoto T, Kobayashi T.   +4 more
europepmc   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5. [PDF]

Oncol Rep
Chen Y, Wei L, Zhang X, Liu X, Chen Y, Zhang S, Zhou L, Li Q, Pan Q, Zhao S, Liu H.   +10 more
europepmc   +1 more source