Results 21 to 30 of about 2,067,066 (317)

Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers

open access: yesNature Genetics, 2020
Extrachromosomal DNA (ecDNA) amplification promotes intratumoral genetic heterogeneity and accelerated tumor evolution1–3; however, its frequency and clinical impact are unclear.
Hoon Kim   +19 more
semanticscholar   +1 more source

Feedback Loop and Bias Amplification in Recommender Systems [PDF]

open access: yesInternational Conference on Information and Knowledge Management, 2020
Recommendation algorithms are known to suffer from popularity bias; a few popular items are recommended frequently while the majority of other items are ignored.
M. Mansoury   +4 more
semanticscholar   +1 more source

Laser microdissection of FFPE tissue areas and subsequent whole genome amplification by Ampli1TM

open access: yes, 2022
S.141-162Laser microdissection (LMD) and whole genome amplification (WGA) are valuable tools to isolate, purify, and genetically analyze cancer cells from tissue sections.
Czyz, Zbigniew Tadeusz   +2 more
core   +1 more source

Neural Plasticity Induced by Hearing Aid Use

open access: yesFrontiers in Aging Neuroscience, 2022
Age-related hearing loss is one of the most prevalent health conditions in older adults. Although hearing aid technology has advanced dramatically, a large percentage of older adults do not use hearing aids.
Hanin Karawani   +2 more
doaj   +1 more source

Generation of Non-uniform support accelerations of topographic site using one recorded accelerogram [PDF]

open access: yesJournal of Structural and Construction Engineering, 2020
This study investigates method of producing non-uniform support acceleration in actual site condition. Factors affecting the non-uniform excitation of topographic site include time delay between the arrival time of incident wave at the canyon floor and ...
Mohsen Isari   +3 more
doaj   +1 more source

Amplification of KCNMA1 : a potential therapeutic target in prostate cancer [PDF]

open access: yes, 2007
Prostate cancer is the most common cancer in males and the second leading cause of cancer deaths in western countries. Although most prostate cancers initially respond well to androgen withdrawal, they become inevitably resistant to this treatment and ...
Bloch, Michael
core   +1 more source

Isothermal Amplification of Nucleic Acids: The Race for the Next “Gold Standard”

open access: yesFrontiers in Sensors, 2021
Nucleic acid amplification technologies (NAATs) have become fundamental tools in molecular diagnostics, due to their ability to detect small amounts of target molecules.
Beatriz Oliveira, B. Veigas, P. Baptista
semanticscholar   +1 more source

Amplified RNA degradation in T7-amplification methods results in biased microarray hybridizations

open access: yesBMC Genomics, 2003
Background The amplification of RNA with the T7-System is a widely used technique for obtaining increased amounts of RNA starting from limited material.
Ivell Richard   +2 more
doaj   +1 more source

The social amplification of risk and the hazard sequence: The October 1995 oral contraceptive pill scare [PDF]

open access: yes, 2003
Hazard notifications routinely occur as part of the identification or management of a hazard. It is argued that a series of such notifications - a hazard sequence - may affect public responses to future notifications about that hazard and also that ...
Barnett, Julie   +3 more
core   +1 more source

Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data

open access: yesNucleic Acids Research, 2009
Despite the central role of quantitative PCR (qPCR) in the quantification of mRNA transcripts, most analyses of qPCR data are still delegated to the software that comes with the qPCR apparatus. This is especially true for the handling of the fluorescence
J. Ruijter   +6 more
semanticscholar   +1 more source

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