Results 21 to 30 of about 1,079,858 (266)

Trends In Amplification [PDF]

open access: yesTrends in Amplification, 2006
The population older than age 65 is increasing and is expected to increase even more in the next 50 years. In the more developed regions of the world, current life expectancy is approximately 76 years, 10 years longer than life expectancy in 1950. By the year 2050, the projected life expectancy will be 82 years.
openaire   +2 more sources

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille   +9 more
wiley   +1 more source

Ways of Time Mythologizing in K.D. Balmont’s Lyrics

open access: yesRUDN Journal of Studies in Literature and Journalism
Time for K. Balmont is not only a moment of experiencing a lyrical emotion in all the entirety of its unique circumstances and the means to express such an emotion, but also the subject of poietic reflection, which attains the form of temporal ...
Olga G. Lazaresku   +1 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

89Zr-labeled ImmunoPET targeting the cancer stem cell antigen CD133 using fully-human antibody constructs

open access: yesEJNMMI Research
Background Cancer stem cells play an important role in driving tumor growth and treatment resistance, which makes them a promising therapeutic target to prevent cancer recurrence.
Kevin Wyszatko   +10 more
doaj   +1 more source

Hate Speech on Trial

open access: yesStudies in Social Justice
Despite the increasing diversity of our online and offline communities, hate speech continues to divide us deeply. We urgently need to examine its ghastly omnipresence and our growing numbness to its harms.
Houman Mehrabian
doaj   +1 more source

Ultimate quantum limit for amplification: a single atom in front of a mirror

open access: yesNew Journal of Physics, 2021
We investigate three types of amplification processes for light fields coupling to an atom near the end of a one-dimensional (1D) semi-infinite waveguide. We consider two setups where a drive creates population inversion in the bare or dressed basis of a
Emely Wiegand   +4 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan   +1 more
wiley   +1 more source

Concepts of Music in Community Music Therapy

open access: yesVoices
This article explores how concepts of music shape music therapy practices, focusing on a three-year-long Community Music Therapy workshop with adolescents at a community center in Argentina. Drawing on theoretical perspectives from Nordoff-Robbins music
Santiago Bertoni
doaj   +1 more source

PD-L1 (CD274) copy number gain, expression, and immune cell infiltration as candidate predictors for response to immune checkpoint inhibitors in soft-tissue sarcoma

open access: yesOncoImmunology, 2017
Soft-tissue sarcomas (STS) are rare malignancies that account for 1% of adult cancers and comprise more than 50 entities. Current therapeutic options for advanced-stage STS are limited. Immune checkpoint inhibitors targeting the PD-1/PD-L1 signaling axis
Jan Budczies   +19 more
doaj   +1 more source

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