Results 101 to 110 of about 270,882 (298)

A high-precision amplifier using ping-pong auto-zeroing

Dianzi Jishu Yingyong
This paper presents the design and implementation of a low-offset, high-gain operational amplifier (op-amp). The overall circuit consists of a bandgap reference, oscillator, frequency divider, auxiliary op-amp, and main op-amp.
Deng Xinwei, Yang Shangzheng, Mao Jiafeng, Hu Weibo, Ren Liru   +4 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Configurable Er-doped core-pumped multi-element fiber amplifier

We demonstrated an Erbium-doped multi-element-fiber amplifier extending the bandwidth at shorter wavelengths in C-band. Each fiber-element provides a maximum gain of 36dB and NF <4dB.
Thipparapu, N.K., May-Smith, T., Jain, S., Sahu, J.K.   +3 more
core   +1 more source

Modelling of two-, threesection TWT of O-type of teraherts band frequencies

Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2016
A analysis of physical processes in TWT on folded waveguide with a consecutive and parallel arrangement of sections concerning electronic beams is carried out. Features and advantages of different construction of amplifiers are noted.
A. V. Aksenchyk, A. A. Kurayev, I. F. Kirinovich   +2 more
doaj  

Bandwidth-Tunable Optical Amplifier with Narrowband Filtering Function Enabled by Parity-Time Symmetry at Exceptional Points

Photonics
Integrated optical amplifiers are the building blocks of on-chip photonic systems, and they are often accompanied by a narrowband filter to limit noise.
Kunpeng Zhu, Xiaoyan Zhou, Yinxin Zhang, Zhanhua Huang, Lin Zhang   +4 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Modeling and optimizing of nonlinear electromagnetic processes. Non-synchronous interaction of free electrons with the electromagnetic radiation field

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
The main results of the researches in the scientific direction «Modeling and optimizing nonlinear electromagnetic processes» for 2013-2018 years are presented.
A. A. Kurayev, V. V. Matveyenka
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

All-optical phase regeneration of 40Gbit/s DPSK signals in a black-box phase sensitive amplifier

We present a black-box four wave mixing based bit-rate-flexible phase sensitive amplifier and use it in the first demonstration of 40 Gbit/s DPSK phase ...
Syvridis, D., Ellis, A.D., Jakobsen, D., Petropoulos, P., O'Gorman, J., Richardson, D.J., Grüner-Nielsen, L., Kakande, J., Weerasuriya, R., Bogris, A., Sygletos, S., Dasgupta, S., Parmigiani, F., Slavík, R., Herstrøm, S., Andrekson, P., Sjödin, M., Lundström, C., Phelan, R.   +18 more
core   +1 more source

Optimizing Shortwave Wideband RF Amplifier: Study of Transmission Line Transformer Construction Methods [PDF]

Radioengineering
This paper presents a study of six physical transmission line transformers (TLTs) designed to provide wideband output matching for laterally diffused metal oxide semiconductor (LDMOS) transistors within a push-pull amplifier operating in the 1.8-30 MHz ...
G. Krupa, G. Budzyn
doaj