Results 121 to 130 of about 270,882 (298)

A low noise cascode amplifier

open access: yes, 1987
We describe the design, schematics, and performance of a very low noise FET cascode input amplifier. This amplifier has noise performance of less than 1.2 nV/Hz and 0.25 fA/Hz over the 500 Hz to 50 kHz frequency range.
Jefferts, S.R.; Walls, F.L.
core   +1 more source

Investigation of in-situ parameter control in novel semiconductor optical amplifiers [PDF]

open access: yes, 2012
Fibre optic networks form the backbone of modern communications systems. As demand for ever increasing bandwidth continues to grow, technologies that enable the expansion of optical networks will be the key to future development.
Carney, Kevin
core   +2 more sources

Cylindrical Vector Beams with an MOPA Amplifier Based on Nonlinear Polarization Rotation Mode-Locking

open access: yesPhotonics
CVBs (cylindrical vector beams) are widely used in optical imaging, optical trapping, material processing, etc. In this study, based on mode-selective couplers and passive mode-locking fiber technology, a cylindrical vector fiber amplifier with an MOPA ...
Tianyu Zhang   +8 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

The design, construction, and testing of a tuned VHF amplifier [PDF]

open access: yes
This thesis deals with the design and construction of a tuned VHF amplifier. The main requirements are that optimum transducer gain must be attempted with a bandwidth of 6 MHz.
Ashley, Anthony, Oryniak, Ken
core  

Intermodulation distortion performance enhancement of microwave power amplifiers [PDF]

open access: yes, 2000
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis reports the author's investigation of the effects of the injection of specific signals on the intermodulation distortion performance of ...
Mbabele, Modeste
core   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Design Low Power 130mW Pipeline ADC With Speed 80 MSPS 8-bit [PDF]

open access: yes, 2009
This paper describes a pipeline analog-to-digital converter is implemented for high speed camera. In the pipeline ADC design, prime factor is designing operational amplifier with high gain so ADC have been high speed.
afandi, Hamzah
core  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

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