Results 71 to 80 of about 220,343 (297)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Low noise buffer amplifiers and buffered phase comparators for precise time and frequency measurement and distribution [PDF]

, 1982
Extremely low noise, high performance, wideband buffer amplifiers and buffered phase comparators were developed. These buffer amplifiers are designed to distribute reference frequencies from 30 KHz to 45 MHz from a hydrogen maser without degrading the ...
Dachel, P., Eichinger, R. A., Ingold, J. S., Miller, W. H.   +3 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Active Antennas Beyond the Standard Impedance Matching Technique: Concepts and Applications

IEEE Open Journal of Antennas and Propagation
This paper presents a new design concept for improving active antennas’ performances beyond the standard impedance matching technique. The proposed approach expands the mismatch at the antenna-amplifier interface to create a voltage excess ...
Constant M. A. Niamien
doaj   +1 more source

Constant-amplitude, frequency- independent phase shifter [PDF]

, 1971
Electronic circuit using operational amplifiers provides output with constant phase shift amplitude, with respect to sinusoidal input, over wide range of frequencies. New circuit includes field effect transistor, Q, operational amplifiers, A1 and A2, and
Deboo, G. J.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Exploring the Development of Teachers’ Personal Pedagogical Content Knowledge about Climate Change Education during a Continuing Teacher Professional Development Course

Southern African Journal of Environmental Education
Climate Change Education (CCE) is widely recognised as one of the effective strategies for mitigating climate change challenges and risks. However, lack of the necessary knowledge and pedagogical skills among the majority of teachers in South Africa ...
Yvonne Nsubuga, Ingrid Schudel, Zintle Songqwaru, Helen Fox   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

A Review on the Flexure-Based Displacement Amplification Mechanisms

IEEE Access, 2020
Multifarious flexure-based displacement amplifiers have been proposed and studied in the past decades, showing importance in many industrial fields, such as bioengineering, optical instruments, and semiconductor technology.
Fangxin Chen, Qianjun Zhang, Yongzhuo Gao, Wei Dong   +3 more
doaj   +1 more source

Input Impedance and Gain of a Gigahertz Amplifier Using a DC SQUID in a Quarter Wave Resonator

, 2008
Due to their superior noise performance, SQUIDs are an attractive alternative to high electron mobility transistors for constructing ultra-low-noise microwave amplifiers for cryogenic use. We describe the use of a lumped element SQUID inductively coupled
Aumentado, Jose, Irwin, Kent, Spietz, Lafe   +2 more
core   +1 more source