Results 61 to 70 of about 35,614 (265)

Exploring the Development of Teachers’ Personal Pedagogical Content Knowledge about Climate Change Education during a Continuing Teacher Professional Development Course

Southern African Journal of Environmental Education
Climate Change Education (CCE) is widely recognised as one of the effective strategies for mitigating climate change challenges and risks. However, lack of the necessary knowledge and pedagogical skills among the majority of teachers in South Africa ...
Yvonne Nsubuga, Ingrid Schudel, Zintle Songqwaru, Helen Fox   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Active Antennas Beyond the Standard Impedance Matching Technique: Concepts and Applications

IEEE Open Journal of Antennas and Propagation
This paper presents a new design concept for improving active antennas’ performances beyond the standard impedance matching technique. The proposed approach expands the mismatch at the antenna-amplifier interface to create a voltage excess ...
Constant M. A. Niamien
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

A Review on the Flexure-Based Displacement Amplification Mechanisms

IEEE Access, 2020
Multifarious flexure-based displacement amplifiers have been proposed and studied in the past decades, showing importance in many industrial fields, such as bioengineering, optical instruments, and semiconductor technology.
Fangxin Chen, Qianjun Zhang, Yongzhuo Gao, Wei Dong   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Prelinearized Class-B Power Amplifier for Piezoelectric Transducers and Portable Ultrasound Systems

Sensors, 2019
Portable ultrasound systems typically suffer from unwanted heat and limited battery life, resulting in reduced system performance or the applicable number of piezoelectric transducer elements.
Hojong Choi
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Amplifying The Uncanny

CoRR, 2020
Deep neural networks have become remarkably good at producing realistic deepfakes, images of people that (to the untrained eye) are indistinguishable from real images. Deepfakes are produced by algorithms that learn to distinguish between real and fake images and are optimised to generate samples that the system deems realistic.
Terence Broad, Frederic Fol Leymarie, Mick Grierson   +2 more
openaire   +3 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source