The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1
ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu +2 more
wiley +1 more source
AI-Driven Real-Time Phase Optimization for Energy Harvesting-Enabled Dual-IRS Cooperative NOMA Under Non-Line-of-Sight Conditions. [PDF]
Al-Ghafri Y +3 more
europepmc +1 more source
ABSTRACT Background Calcium silicate sealers (CSS) have become the dominant approach to root canal obturation in many specialist practices, yet evidence on their performance in nonsurgical retreatment is sparse and CBCT‐based assessment remains uncommon.
Ahmad Aldowaisan +6 more
wiley +1 more source
Secrecy outage probability and strictly positive secrecy capacity of UAV assisted cooperative NOMA system with two untrusted destinations. [PDF]
Khan MJ, Ahmad S, Singh I, Sahu UK.
europepmc +1 more source
A Quantile Model of Firm Investment
ABSTRACT Are firms risk averse? We propose a dynamic model of firm investment under uncertainty that captures firms' risk attitudes through quantile preferences. The firm maximizes its present value, defined as current profits and investment plus the discounted value of the τ$\tau$‐quantile of its value next period.
Heitor Almeida +3 more
wiley +1 more source
Oculofacial plastic surgery fellowship director perspectives on accreditation council for graduate medical education (ACGME) accreditation. [PDF]
Fujihashi A +6 more
europepmc +1 more source
Summary Understanding the spread of infectious diseases such as COVID‐19 is crucial for informed decision‐making and resource allocation. A critical component of disease behaviour is the velocity with which disease spreads, defined as the rate of change between time and space.
Fernando Rodriguez Avellaneda +2 more
wiley +1 more source
A Novel SXXLF Motif in the FXR N-Terminal Domain Mediates Coregulator and Interdomain Interactions. [PDF]
Villalona P +8 more
europepmc +1 more source
Equal Access, Unequal Investment: Gender Differences in Workplace Training Intensity
ABSTRACT Gender differences in access to workplace training have narrowed in many countries, and training participation rates are commonly used to assess equality in skill development. However, participation rates alone do not capture how much training employees receive.
Bonwoo Koo, Jangho Yang, Brian Cozzarin
wiley +1 more source
Antithrombotic Therapy After PCI in High-Risk Cardiovascular Patients: Navigating Complexity Beyond Guidelines. [PDF]
Veneziano FA, De Luca L.
europepmc +1 more source

