Results 91 to 100 of about 375,907 (328)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Power Scaling Laws of Massive MIMO Full-Duplex Relaying With Hardware Impairments
IEEE Access, 2018 This paper considers a massive MIMO full-duplex relaying (FDR) system, in which multiple single-antenna sources simultaneously communicate with multiple single-antenna destinations using a single relay that is equipped with Ntx transmit antennas and Nrx ...
Si-Nian Jin, Dian-Wu Yue, Ha H. Nguyen
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Multiple Access Channels With Full-Duplex Amplify-and-Forward Transmitter Cooperations
IEEE Access, 2019 In this paper, a full-duplex (FD) transmitter cooperative scheme is proposed to improve the achievable rate for multiple access channels (MACs). In the proposed scheme, by leveraging the FD amplify-and-forward (AF) protocol, two FD transmitters send ...
Qingpeng Liang, Donglin Liu, Chuan Huang
doaj +1 more source
Large N Analysis of Amplify-and-Forward MIMO Relay Channels with Correlated Rayleigh Fading [PDF]
, 2006 Joerg Wagner +2 more
openalex +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Asymptotic Outage Probability Analysis for General Fixed-Gain Amplify-and-Forward Multihop Relay Systems [PDF]
, 2012 Justin P. Coon, Yue Wang, Gillian Huang
openalex +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source