Results 71 to 80 of about 148,461 (296)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Interference Channel With Full-Duplex Amplify-and-Forward Transmitter Cooperations
IEEE Access, 2019 This paper considers a Gaussian interference channel (IC), where two transmitters send two messages to two receivers respectively. By utilizing the in-band full-duplex (FD) amplify-and-forward (AF) scheme, transmitter cooperations are deployed to enhance
Jianhao Huang, Dan Wang, Chuan Huang
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
SINR Maximizing Beamforming Schemes for the Full Duplex Amplify-and-Forward Relay Channel
IEEE Access, 2017 We propose signal-to-interference-plus-noise power ratio (SINR) maximizing rank one beamforming schemes for the full-duplex (FD) relay systems. The non-regenerative amplify and forward (AaF) relay is considered with multiple transmit antennas and ...
Duckdong Hwang +2 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Noncoherent Multi-Way Relay Based on Fast Frequency-Hopping M-ary Frequency-Shift Keying [PDF]
, 2010 Information exchange among a group of users is implemented with the aid of fast frequency-hopping $M$-ary frequency-shift keying multi-way relay (FFH/MFSK MWR). The FFH/MFSK MWR scheme uses two time-slots per symbol for achieving the information exchange,
Cao, Jianfei +2 more
core +2 more sources
ABUAD Journal of Engineering Research and DevelopmentWireless communication system is crucial to telecommunications infrastructure and has played an essential role in national growth. However, the system's performance is hindered by multipath propagation, which has negatively impact in its performance ...
Samson Iyanda OJO +4 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Covert Communications in a Hybrid DF/AF Relay System
SensorsIn this paper, we study covert communications in a hybrid decode-and-forward (DF)/ amplify-and-forward (AF) relay system. The considered relay in normal operation forwards messages from a source node to a destination node in either DF or AF mode on ...
Jihwan Moon
doaj +1 more source