Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Optimal relay selection scheme and outage probability analysis in cooperative wireless networks
Optimal relay selection can effectively improve the system performance in the communication network with cooperative relays from the view of physical layer security.The optimal relay selection schemes for relay transmission system with multiple single ...
Youhong FENG +5 more
doaj +2 more sources
Adaptive AF/DF Selection With FD/HD Switching in Two-Way Relay Networks
The full-duplex (FD) and two-way relay are promising techniques for their high spectrum efficiency. However, the incompletely self-interference cancellation may reduce the performance gain of two-way relay networks, which operates in FD mode.
Quanqiang Miao, Bo Bai, Wei Chen
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Incremental selection amplify-and-forward relaying (ISAF) has the best performance of outage probability among relaying strategies and has been identified as the best protocol.
Xiang, Wei +9 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Enhanced Amplify-and-Forward Relaying in Non-Gaussian PLC Networks
Relaying over power line communication (PLC) channels has the potential to improve the reliability and robustness of many PLC-based applications. In particular, this paper proposes to enhance the energy efficiency (EE) of a dual-hop relaying PLC system ...
Khaled M. Rabie, Bamidele Adebisi
doaj +1 more source
Physical layer multicasting over 2-hop network using dual amplify and forward relay
The inherent multicast nature of the wireless medium can be exploited over two hop networks paves a way for Physical layer multicasting. The system performance gain can be achieved through multicast diversity achieved with dual amplify-and-forward (AF ...
Xiang, Wei +9 more
core +1 more source

