Results 61 to 70 of about 134,511 (264)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

SINR Maximizing Beamforming Schemes for the Full Duplex Amplify-and-Forward Relay Channel

IEEE Access, 2017
We propose signal-to-interference-plus-noise power ratio (SINR) maximizing rank one beamforming schemes for the full-duplex (FD) relay systems. The non-regenerative amplify and forward (AaF) relay is considered with multiple transmit antennas and ...
Duckdong Hwang, Janghoon Yang, Sung Sik Nam   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

EMD-Based Amplify Quantized and Forward Cooperative Relaying Technique for Wireless Communication System

ABUAD Journal of Engineering Research and Development
Wireless communication system is crucial to telecommunications infrastructure and has played an essential role in national growth. However, the system's performance is hindered by multipath propagation, which has negatively impact in its performance ...
Samson Iyanda OJO, James Oluwatomisin Oladapo, Robert Oluwayimika Abolade, Isaac Adewale Ojedokun, Oluwatobi Omolola Oyedokun   +4 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Covert Communications in a Hybrid DF/AF Relay System

Sensors
In this paper, we study covert communications in a hybrid decode-and-forward (DF)/ amplify-and-forward (AF) relay system. The considered relay in normal operation forwards messages from a source node to a destination node in either DF or AF mode on ...
Jihwan Moon
doaj   +1 more source

Efficient Simulation of the Outage Probability of Multihop Systems

IEEE Photonics Journal, 2017
In this paper, we present an efficient importance sampling estimator for the evaluation of the outage probability of multihop systems with amplify-and-forward channel state-information-assisted. The proposed estimator is endowed with the bounded relative
Chaouki Ben Issaid, Mohamed-Slim Alouini, Raul Tempone   +2 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Cooperative Terrestrial-Underwater Wireless Optical Links by Using an Amplify-and-Forward Strategy. [PDF]

Sensors (Basel), 2022
Jurado-Navas A, Álvarez-Roa C, Álvarez-Roa M, Castillo-Vázquez M.   +3 more
europepmc   +1 more source