Results 61 to 70 of about 3,698,626 (376)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Журнал інженерних наук, 2019 The comparison results of the hardness measuring of welded metal and the heat-affected zone of the eight welded beads from low-carbon steel obtained by surfacing CO2/MAG with welding bath oscillation influence at values of amplitude equaled 0.5 mm ...
Lebedev V. A. +2 more
doaj +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
APL PhotonicsIn the last decades, nonlinear optical microscopy techniques, such as two-Photon Excited Fluorescence (2PEF), Sum Frequency Generation (SFG), and Hyperspectral Coherent Anti-Stokes Raman Scattering (H-CARS) microscopy, emerged as powerful tools to image ...
Federico Vernuccio +10 more
doaj +1 more source
Development of difference spectrophotometric method for the estimation of leflunomide in tablet dosage form [PDF]
Chemical Industry and Chemical Engineering Quarterly, 2012 A new simple, accurate, precise, highly sensitive and reproducible difference spectrophotometric method for the determination of leflunomide in bulk and pharmaceutical dosage form is described. Difference spectroscopic method is based on the principle
Lakshmana Prabu S. +2 more
doaj +1 more source
Physical Simulation of Ultrasonic Imaging Logging Response
Sensors, 2022 Ultrasonic imaging logging can visually identify the location, shape, dip angle and orientation of fractures and holes. The method has not been effectively applied in the field; one of the prime reasons is that the results of physical simulation ...
Junqiang Lu +6 more
doaj +1 more source
Period-Amplitude Co-variation in Biomolecular Oscillators
, 2018 The period and amplitude of biomolecular oscillators are functionally important properties in multiple contexts. For a biomolecular oscillator, the overall constraints in how tuning of amplitude affects period, and vice versa, are generally unclear. Here
Bokka, Venkat +2 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
MicromachinesIn this contribution, we present novel results on top-down drilling in silicon, the most important semiconductor material, focusing specifically on the influence of the laser parameters.
Pierre Balage +6 more
doaj +1 more source
Complete N-Point Superstring Disk Amplitude II. Amplitude and Hypergeometric Function Structure [PDF]
, 2011 Using the pure spinor formalism in part I [1] we compute the complete tree-level amplitude of N massless open strings and find a striking simple and compact form in terms of minimal building blocks: the full N-point amplitude is expressed by a sum over ...
Mafra, Carlos R. +2 more
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