Results 71 to 80 of about 42,651 (303)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Large variation in the boundary-condition slippage for a rarefied gas flowing between two surfaces
, 2011 We study the slippage of a gas along mobile rigid walls in the sphere-plane confined geometry and find that it varies considerably with pressure. The classical no-slip boundary condition valid at ambient pressure changes continuously to an almost perfect
Chevrier, J. +4 more
core +3 more sources
A survey on OFDM-based elastic core optical networking [PDF]
, 2013 Orthogonal frequency-division multiplexing (OFDM) is a modulation technology that has been widely adopted in many new and emerging broadband wireless and wireline communication systems.
De Leenheer, Marc +3 more
core +2 more sources
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
Symmetry effects and equivalences in lattice models of hydrophobic interaction
, 2000 We establish the equivalence of a recently introduced discrete model of the hydrophobic interaction, as well as its extension to continuous state variables, with the Ising model in a magnetic field with temperature-dependent strength. In order to capture
B. Widom +11 more
core +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Blur point versus indistinguishable point in assessment of accommodation: objective and subjective findings in early presbyopes [PDF]
, 2003 Aim: To measure the distance from the eye and the refraction of the eye at the point at which print blurs and the point at which it becomes unreadable. Methods: Subjective accommodation in 7 early presbyopic subjects (mean age 45 years), with no
Firth, A.Y., Goodall, E.
core
Creating effective focus cues in multi-plane 3D displays. [PDF]
, 2011 Focus cues are incorrect in conventional stereoscopic displays. This causes a dissociation of vergence and accommodation, which leads to visual fatigue and perceptual distortions.
Akeley, Kurt +2 more
core +2 more sources