Results 61 to 70 of about 29,731 (231)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Frequency-specific alterations of fractional amplitude of low-frequency fluctuations in adult-onset hypothyroidism

Journal of Integrative Neuroscience, 2023
AbstractPurpose Abnormal spontaneous neuronal activities associated with cognitive deficits and emotional dysfunction were found in hypothyroidism. However, routine method employs a relatively broader range of spontaneous fluctuations and would mingle physiological fluctuations contained in specific frequency. In current study we explored how frequency-
Lianping Zhao, Jiancang Cao, Rui Qin, Limin Tian, Gang Huang, Jing Tian, Yalan Han, Qian Shi   +7 more
openaire   +3 more sources

Amplitude of low-frequency fluctuations in classical trigeminal neuralgia patients with purely paroxysmal and concomitant continuous pain

Frontiers in Pain Research
BackgroundPurely paroxysmal neuralgia (PP-CTN) and concomitant continuous pain (CCP-CTN) are different subtypes of classical trigeminal neuralgia (CTN).
He Zhao, Shenghui Xie, Xueying Ma, Xue Bai, Yuanjun Song, Qiong Wu, Yang Gao   +6 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Altered amplitude of low-frequency fluctuation and regional cerebral blood flow in females with primary dysmenorrhea: a resting-state fMRI and arterial spin labeling study

Journal of Pain Research, 2019
Ya-Nan Zhang,1 Jian-Wei Huo,1 Yi-Ran Huang,2 Ying Hao,3 Zi-Yue Chen41Department of Radiology, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, People’s Republic of China; 2School of ...
Zhang YN, Huo JW, Huang YR, Hao Y, Chen ZY   +4 more
doaj  

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Response of a stretched cylindrical diffusion flame to a sinusoidal velocity oscillation of air stream

Nihon Kikai Gakkai ronbunshu, 2017
Experimental study was performed to reveal the response characteristics of a stretched cylindrical diffusion flame to sinusoidal oscillation of air flow velocity.
Yosuke SUENAGA, Hideki YANAOKA, Mamoru KIKUCHI, Shun SASAKI   +3 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Suppression of Low-Frequency Shock Oscillations over Boundary Layers by Repetitive Laser Pulse Energy Deposition

Aerospace, 2016
The effect of repetitive energy deposition on low Strouhal number oscillations of the shock wave induced by boundary-layer interaction over a cylinder-flare model was studied.
Akira Iwakawa, Tatsuro Shoda, Hoang Son Pham, Takahiro Tamba, Akihiro Sasoh   +4 more
doaj   +1 more source