Results 91 to 100 of about 29,753 (243)

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Dynamic alterations in spontaneous neural activity in patients with attention-deficit/hyperactivity disorder: A resting-state fMRI study

Brain Research Bulletin
Background: To investigate the change of dynamic amplitude of low-frequency fluctuation (dALFF) and dynamic fractional amplitude of low-frequency fluctuation (dfALFF) in patients with attention-deficit/hyperactivity disorder (ADHD), and to explore ...
Rui Hu, Wei Du, Fan Tan, Yong Wu, Chun Yang, Weiwei Wang, Wen Chen, Yanwei Miao   +7 more
doaj   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Frequency-dependent changes in the amplitude of low-frequency fluctuations in post stroke apathy: a resting-state fMRI study

Frontiers in Psychiatry
BackgroundApathy is a prevalent psychiatric condition after stroke, affecting approximately 30% of stroke survivors. It is associated with slower recovery and an increased risk of depression. Understanding the pathophysiological mechanisms of post stroke
Ying Liu, Ying Liu, Yi-Kuang Hsien, Yi-Kuang Hsien, Wenlong Su, Wenlong Su, Zhiqing Tang, Zhiqing Tang, Hui Li, Junzi Long, Junzi Long, Xingxing Liao, Xingxing Liao, Hao Zhang, Hao Zhang, Hao Zhang   +15 more
doaj   +1 more source

Exploration of intrinsic brain activity in migraine with and without comorbid depression

The Journal of Headache and Pain, 2018
Background Major depressive disorder is a common comorbidity in migraineurs. Depression may affect the progression and prognosis of migraine. Few studies have examined the brain function in migraineurs that may cause this comorbidity.
Mengmeng Ma, Junran Zhang, Ning Chen, Jian Guo, Yang Zhang, Li He   +5 more
doaj   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Amplitude of low-frequency fluctuations in childhood-onset schizophrenia with or without obsessive-compulsive symptoms: a resting-state functional magnetic resonance imaging study

Archives of Medical Science, 2018
Introduction Childhood-onset schizophrenia with obsessive-compulsive symptoms (COSO) and without obsessive-compulsive symptoms (COS) share considerable overlap in clinical features and genetic risk factors.
Yinghui Liang, Rongrong Shao, Zhiying Zhang, Xinmin Li, Longhao Zhou, Suqin Guo   +5 more
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Assessment of alterations in regional homogeneity and amplitude of low-frequency fluctuations in children with dyslexia ​

Turkish Journal of Medical Sciences
Background/aim: Exploratory methods in neuroimaging are gaining increasing attention for revealing functional connectivity structures across the entire brain. This study aims to contribute to the understanding of the functional mechanisms underlying dyslexia, along with the effects of specialized education for dyslexia treatment, by utilizing measures ...
DEMİRCİ, Esra, GENGEÇ BENLİ, Şerife, İÇER, Semra, AK, Zeynep, AKER, Ebru, KARAMAN, Zehra Filiz   +5 more
openaire   +2 more sources