Results 71 to 80 of about 173,658,569 (246)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Alterations of amplitude of low-frequency fluctuation in treatment-resistant versus non-treatment-resistant depression patients

Neuropsychiatric Disease and Treatment, 2019
Aixia Zhang,1,2 Gaizhi Li,1 Chunxia Yang,1 Penghong Liu,2 Yanfang Wang,1 Lijun Kang,2 Yuchen Wang,2 Kerang Zhang11Department of Psychiatry, First Hospital of Shanxi Medical University, Taiyuan 030001, People’s Republic of China; 2Shanxi ...
Zhang A, Li G, Yang C, Liu P, Wang Y, Kang L, Wang Y, Zhang K   +7 more
doaj  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

fALFF interaction area as the picture shows were cerebellum, Middle Temporal, and sup-motor (P<0.05, AlphaSim corrected).

, 2021
fALFF, the fractional amplitude of low-frequency fluctuation.
Fangmei He (11273133), Youjun Li (248448), Tian Liu (78007), Chenxi Li (1459123), Liming Fan (693731), Jue Wang (58890)   +5 more
core   +1 more source

Altered Temporal Dynamics of the Amplitude of Low-Frequency Fluctuations in Comitant Exotropia Patients

Frontiers in Human Neuroscience, 2022
PurposeGrowing evidence reported that patients with comitant exotropia (CE) were accompanied by static cerebral neural activity changes. However, whether the dynamic time-varying of neural activity changes in patients with CE remains unknown.MethodsA total of 36 patients with CE (25 men and 11 women) and 36 well-matched healthy controls are enrolled in
Ri-Bo Chen, Shu-Yuan Ye, Chong-Gang Pei, Yu-Lin Zhong   +3 more
openaire   +3 more sources

Amplitude of low-frequency fluctuations in classical trigeminal neuralgia patients with purely paroxysmal and concomitant continuous pain

Frontiers in Pain Research
BackgroundPurely paroxysmal neuralgia (PP-CTN) and concomitant continuous pain (CCP-CTN) are different subtypes of classical trigeminal neuralgia (CTN).
He Zhao, Shenghui Xie, Xueying Ma, Xue Bai, Yuanjun Song, Qiong Wu, Yang Gao   +6 more
doaj   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

The response of a conical flame to a dual-frequency excitation

, 2023
This work investigates the response of a conical premixed flame to a dual-frequency excitation, based on the integrated CH* signal collected from a photomultiplier tube (PMT), the upstream velocity disturbance measured by a hotwire, and the ...
XU, Liangliang, Wang, Sirui, Wang, Guoqing, QI, Fei, Xia, Xi, ZHENG, Jianyi, Li, Lei   +6 more
core   +1 more source

Reliability of the amplitude of low-frequency fluctuations in resting state fMRI in chronic schizophrenia [PDF]

Psychiatry Research: Neuroimaging, 2012
The resting state amplitude of low frequency fluctuations (ALFF) in functional magnetic resonance imaging has been shown to be reliable in healthy subjects, and to correlate with antipsychotic treatment response in antipsychotic-naïve schizophrenia patients.
Jessica A, Turner, Hongji, Chen, Daniel H, Mathalon, Elena A, Allen, Andrew R, Mayer, Christopher C, Abbott, Vince D, Calhoun, Juan, Bustillo   +7 more
openaire   +2 more sources

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source