AmpR ofStenotrophomonas maltophiliais involved in stenobactin synthesis and enhanced β-lactam resistance in an iron-depleted condition [PDF]
AbstractBackgroundIron is an essential nutrient for almost all aerobic organisms, including Stenotrophomonas maltophilia. Fur is the only known transcriptional regulator presumptively involved in iron homeostasis in S. maltophilia. AmpR, a LysR-type transcriptional regulator, is known to regulate β-lactamase expression and β-lactam resistance in S ...
Chun‐Hsing Liao +5 more
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Introducing AMPR technique for zero crossing bandwidth expansion in outphasing PA [PDF]
Outphasing systems utilize radio-frequency high-efficiency Power Amplifiers (PAs). Here we analyze impairment distortion as result of Signal Component Separator (SCS) that accounts for most of the nonlinearities in outphasing systems. Phase modulation is the general canonical form for the SCS process, which generates two constant envelope outphased ...
Somayeh Mohammady, Pavel Afanasyev
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Investigation of thePseudomonas aeruginosa ampRgene and its role at the chromosomalampCβ-lactamase promoter [PDF]
The complete sequence of the Pseudomonas aeruginosa beta-lactamase regulator gene ampR has been determined. The amino acid sequence encoded by this gene is compared with other members of the LysR family of transcription factors. The P. aeruginosa ampC promoter was subcloned and gel mobility shift assays were used to demonstrate specific binding of AmpR
Julia Lodge +2 more
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Cloning, Sequence Analyses, Expression, and Distribution of ampC-ampR from Morganella morganii Clinical Isolates [PDF]
ABSTRACT Shotgun cloning experiments with restriction enzyme-digested genomic DNA from Morganella morganii 1, which expresses high levels of cephalosporinase, into the pBKCMV cloning vector gave a recombinant plasmid, pPON-1, which encoded four entire genes: ampC , ampR
Laurent Poirel +4 more
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The rapid acquisition of antibiotic resistance of Pseudomonas aeruginosa has been a complex problem in clinics. Two meropenem-resistant P. aeruginosa isolates were collected from the same patient on May 24, 2021, and June 4, 2021, respectively. The first
Li Ding +4 more
doaj +1 more source
To overcome increasing bacterial resistance to conventional antibiotics, many antimicrobial peptides (AMPs) derived from host defense proteins have been developed.
Hye-Ra Lee +7 more
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CFE-1, a Novel Plasmid-Encoded AmpC β-Lactamase with anampRGene Originating fromCitrobacter freundii [PDF]
ABSTRACTA clinical isolate ofEscherichia colifrom a patient in Japan, isolate KU6400, was found to produce a plasmid-encoded β-lactamase that conferred resistance to extended-spectrum cephalosporins and cephamycins. Resistance arising from production of a β-lactamase could be transferred by either conjugation or transformation with plasmid pKU601 intoE.
Ryuichi Nakano +6 more
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Enhanced deoxyviolacein bioproduction via enzyme condensation with a yeast glycolytic enzyme-derived peptide tag. [PDF]
Fusion of a 27‐amino‐acid peptide tag derived from a glycolytic enzyme enabled artificial assembly formation of the two violacein biosynthetic enzymes, VioE and VioC. This assembly resulted in enhanced biosynthesis of deoxyviolacein. Abstract In microbial production, regulating endogenous and exogenous synthetic pathways is essential.
Ito R +4 more
europepmc +2 more sources
ampR Gene Mutations That Greatly Increase Class C β-Lactamase Activity in Enterobacter cloacae [PDF]
ABSTRACT The ampC and ampR genes of Enterobacter cloacae GN7471 were cloned into pMW218 to yield pKU403. Four mutant plasmids derived from pKU403 (pKU404, pKU405, pKU406, and pKU407) were isolated in an AmpD mutant of Escherichia coli ...
Akio Kuga +2 more
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Multidrug-resistant (MDR) Enterococcus faecium (Efm) infections continue to increase worldwide, although epidemiological studies remain scarce in lower middle-income countries. We aimed to explore which strains circulate in E.
Ana R. Freitas +8 more
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