Results 51 to 60 of about 28,237 (223)

Multiple pathways of plasmid DNA transfer in Helicobacter pylori [PDF]

open access: yes, 2012
Many Helicobacter pylori (Hp) strains carry cryptic plasmids of different size and gene content, the function of which is not well understood. A subgroup of these plasmids (e.g.
Benghezal, Mohammed   +5 more
core   +3 more sources

In vivo and in vitro characterization of Staphylococcus aureus and Bacillus subtilis polyglycerolphosphate lipoteichoic acid synthases [PDF]

open access: yes, 2011
Staphylococcus aureus lipoteichoic acid (LTA) consists of a 1,3-linked polyglycerolphosphate chain retained in the bacterial membrane by a glycolipid anchor.
Wörmann, Mirka Elisabeth   +1 more
core   +1 more source

Screening for AmpR-Specific Inhibitors to Combat P. aeruginosa Infections [PDF]

open access: green, 2015
Pseudomonas aeruginosa, a Gram-negative bacterium, an opportunistic pathogen that infects individuals suffering from reduced immunity or damaged tissue.
Kevin Morales
openalex   +2 more sources

Deletion of Lytic Transglycosylases Increases Beta-Lactam Resistance in Shewanella oneidensis

open access: yesFrontiers in Microbiology, 2018
Production of chromosome-encoded β-lactamases confers resistance to β-lactams in many Gram-negative bacteria. Some inducible β-lactamases, especially the class C β-lactamase AmpC in Enterobacteriaceae, share a common regulatory mechanism, the ampR-ampC ...
Jianhua Yin   +7 more
doaj   +1 more source

Cryptic transcripts from a ubiquitous plasmid origin of replication confound tests for cis-regulatory function. [PDF]

open access: yes, 2012
A vast amount of research on the regulation of gene expression has relied on plasmid reporter assays. In this study, we show that plasmids widely used for this purpose constitutively produce substantial amounts of RNA from a TATA-containing cryptic ...
Hiraoka, Kei   +3 more
core   +2 more sources

Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond

open access: yesBMEMat, EarlyView.
Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad   +8 more
wiley   +1 more source

Surmounting Recalcitrant Airway Inflammatory Disorders With a Multi‐Targeting Therapeutic Strategy by Tannic Acid‐Modified CuInP2S6 Nanosheets

open access: yesExploration, EarlyView.
Our findings underscore a multi‐targeting strategy for severe airway inflammation that multi‐targeting nanoformulation C‐TA1 markedly attenuated airway inflammation by (1) cfDNA elimination to alleviate neutrophilic/eosinophilic inflammation mediated by the TLR9 pathway, (2) prevention of RONS‐induced tissue injury and inflammatory response, (3 ...
Ming Liu   +10 more
wiley   +1 more source

Snapshots of Motion: A Novel Structural Intermediate Reveals Conserved Dynamics in Archaeal DNA Ligases

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas   +3 more
wiley   +1 more source

Identificación de servicios de los ecosistemas en comunidades asociadas a tres áreas marinas de pesca responsable del Golfo de Nicoya, Costa Rica

open access: yesAbra, 2021
Los servicios de los ecosistemas son fundamentales para la supervivencia del ser humano y su reconocimiento por parte de las comunidades constituye un primer paso hacia un aprovechamiento sostenible de estos.
Valeria Umaña Blanco   +1 more
doaj  

SanA Plays a Role in Peptidoglycan Integrity in Escherichia coli

open access: yesMolecular Microbiology, EarlyView.
SanA is a novel regulator of peptidoglycan synthesis, potentially through functional interplay with PBP1B‐dependent pathways. ABSTRACT Peptidoglycan synthesis and degradation are both essential for bacterial growth, and damaged peptidoglycan must be continuously repaired. In Escherichia coli, peptidoglycan required for cell elongation is synthesized by
Honoka Yamaguchi   +6 more
wiley   +1 more source

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