Results 1 to 10 of about 326,817 (387)

Transtibial limb loss does not increase metabolic cost in three-dimensional computer simulations of human walking [PDF]

PeerJ, 2021
Loss of a lower limb below the knee, i.e., transtibial limb loss, and subsequently walking with a prosthesis, is generally thought to increase the metabolic cost of walking vs. able-bodied controls.
Ross H. Miller, Elizabeth Russell Esposito   +1 more
doaj   +2 more sources

Prolonged field care for traumatic extremity injuries: defining a role for biologically focused technologies

npj Regenerative Medicine, 2021
Extremity injuries occur frequently during warfare. While traditionally treated in definitive clinics, the future battlefield is projected to be different in a variety of ways, and there will likely be a shift towards prolonged field care (PFC) for ...
Connor P. Dolan, Michael S. Valerio, W. Lee Childers, Stephen M. Goldman, Christopher L. Dearth   +4 more
doaj   +1 more source

The impact of bilateral injuries on the pathophysiology and functional outcomes of volumetric muscle loss

npj Regenerative Medicine, 2022
Volumetric muscle loss (VML)—defined as the irrecoverable loss of skeletal muscle tissue with associated persistent functional deficits—is among the most common and highly debilitating combat-related extremity injuries. This is particularly true in cases
Connor P. Dolan, Andrew R. Clark, Jessica M. Motherwell, Naveena B. Janakiram, Michael S. Valerio, Christopher L. Dearth, Stephen M. Goldman   +6 more
doaj   +1 more source

Retrospective characterization of a rat model of volumetric muscle loss

BMC Musculoskeletal Disorders, 2022
Volumetric muscle loss (VML) is a pervasive injury within contemporary combat and a primary driver of disability among injured Service members. As such, VML has been a topic of investigation over the past decade as the field has sought to understand the ...
Connor P. Dolan, Christopher L. Dearth, Benjamin T. Corona, Stephen M. Goldman   +3 more
doaj   +1 more source

Development and characterization of an intra‐articular fracture mediated model of post‐traumatic osteoarthritis

Journal of Experimental Orthopaedics, 2023
Purpose This study aimed to develop and characterize a closed intra‐articular fracture (IAF) mediated post‐traumatic osteoarthritis (PTOA) model in rats to serve as a testbed for putative disease modifying interventions. Methods Male rats were subject to
Michael S. Valerio, William A. Pace, Connor P. Dolan, Jorge B. Edwards, Naveena B. Janakiram, Benjamin K. Potter, Christopher L. Dearth, Stephen M. Goldman   +7 more
doaj   +1 more source

In situ forming biomaterials as muscle void fillers for the provisional treatment of volumetric muscle loss injuries

Materials Today Bio, 2023
Volumetric muscle loss (VML) represents a devastating extremity injury which leads to chronic functional deficits and disability and is unrecoverable through normal healing pathways.
Andrew Clark, Jonathan Kulwatno, Sergey S. Kanovka, Todd O. McKinley, Benjamin K. Potter, Stephen M. Goldman, Christopher L. Dearth   +6 more
doaj   +1 more source

Exoskeletal solutions to enable mobility with a lower leg fracture in austere environments

Wearable Technologies, 2023
The treatment and evacuation of people with lower limb fractures in austere environments presents unique challenges that assistive exoskeletal devices could address.
W. Brett Johnson, Aaron Young, Stephen Goldman, Jon Wilson, Joseph F. Alderete, W. Lee Childers   +5 more
doaj   +1 more source

Pre-neuromusculoskeletal injury Risk factor Evaluation and Post-neuromusculoskeletal injury Assessment for Return-to-duty/activity Enhancement (PREPARE) in military service members: a prospective, observational study protocol

Journal of Translational Medicine, 2022
Background Non-battle related musculoskeletal injuries (MSKI) are one of the primary medical issues diminishing Service member medical readiness. The MSKI problem is challenging because it is difficult to assess all of the factors that increase MSKI risk
Courtney M. Butowicz, Brad D. Hendershot, Nora L. Watson, Daniel I. Brooks, Donald L. Goss, Robert A. Whitehurst, Alisha D. Harvey, Matthew S. Helton, Joseph R. Kardouni, Matthew B. Garber, Timothy C. Mauntel   +10 more
doaj   +1 more source

Repurposing existing products to accelerate injury recovery (REPAIR) of military relevant musculoskeletal conditions

Frontiers in Bioengineering and Biotechnology, 2023
Musculoskeletal injuries (MSKIs) are a great hindrance to the readiness of the United States Armed Forces through lost duty time and reduced operational capabilities.
Andrew R. Clark, Andrew R. Clark, Timothy C Mauntel, Timothy C Mauntel, Timothy C Mauntel, Stephen M Goldman, Stephen M Goldman, Christopher L. Dearth, Christopher L. Dearth   +8 more
doaj   +1 more source

Osseointegration Following Transfemoral Amputation After Infected Total Knee Replacement: A Case Series of 10 Patients With a Mean Follow-up of 5 Years

Arthroplasty Today, 2022
Background: Management of total knee replacement (TKR) infection may sometimes prompt knee fusion (KF) or transfemoral amputation (TFA), both associated with low mobility and quality of life (QOL).
Muhammad Adeel Akhtar, MBBS, FRCSEd, Jason Shih Hoellwarth, MD, Kevin Tetsworth, MD, FRACS, Atiya Oomatia, BEng Biomedical, Munjed Al Muderis, MB, ChB, FRACS   +4 more
doaj   +1 more source