Results 1 to 10 of about 324,346 (384)

Geographic and Socioeconomic Disparities in Major Lower Extremity Amputation Rates in Metropolitan Areas

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Rates of major lower extremity amputation in patients with peripheral artery disease are higher in rural communities with markers of low socioeconomic status, but most Americans live in metropolitan areas.
Alexander C. Fanaroff   +12 more
doaj   +2 more sources

Predictors for Amputation in Patients with Diabetic Foot Wound

open access: yesVascular Specialist International, 2018
Purpose: Diabetic foot wound (DFW) is known as a major contributor of nontraumatic lower extremity amputation. We aimed to evaluate overall amputation rates and risk factors for amputation in patients with DFW. Materials and Methods: From January 2014
Se-Young Kim   +8 more
doaj   +2 more sources

Mortality after major amputation in elderly patients with critical limb ischemia

open access: yesClinical Interventions in Aging, 2017
Sanne Klaphake,1,2 Kevin de Leur,1 Paul GH Mulder,1,3 Gwan H Ho,1 Hans G de Groot,1 Eelco J Veen,1 Hence JM Verhagen,2 Lijckle van der Laan1 1Department of Surgery, Amphia Hospital, Breda, 2Department of Vascular Surgery, Erasmus University Medical ...
Klaphake S   +7 more
doaj   +2 more sources

Transtibial limb loss does not increase metabolic cost in three-dimensional computer simulations of human walking [PDF]

open access: yesPeerJ, 2021
Loss of a lower limb below the knee, i.e., transtibial limb loss, and subsequently walking with a prosthesis, is generally thought to increase the metabolic cost of walking vs. able-bodied controls.
Ross H. Miller   +1 more
doaj   +2 more sources

Prolonged field care for traumatic extremity injuries: defining a role for biologically focused technologies

open access: yesnpj Regenerative Medicine, 2021
Extremity injuries occur frequently during warfare. While traditionally treated in definitive clinics, the future battlefield is projected to be different in a variety of ways, and there will likely be a shift towards prolonged field care (PFC) for ...
Connor P. Dolan   +4 more
doaj   +1 more source

An explainable machine learning model for predicting in‐hospital amputation rate of patients with diabetic foot ulcer

open access: yesInternational Wound Journal, 2021
Diabetic foot ulcer (DFU) is one of the most serious and alarming diabetic complications, which often leads to high amputation rates in diabetic patients.
Puguang Xie   +10 more
semanticscholar   +1 more source

The impact of bilateral injuries on the pathophysiology and functional outcomes of volumetric muscle loss

open access: yesnpj Regenerative Medicine, 2022
Volumetric muscle loss (VML)—defined as the irrecoverable loss of skeletal muscle tissue with associated persistent functional deficits—is among the most common and highly debilitating combat-related extremity injuries. This is particularly true in cases
Connor P. Dolan   +6 more
doaj   +1 more source

Retrospective characterization of a rat model of volumetric muscle loss

open access: yesBMC Musculoskeletal Disorders, 2022
Volumetric muscle loss (VML) is a pervasive injury within contemporary combat and a primary driver of disability among injured Service members. As such, VML has been a topic of investigation over the past decade as the field has sought to understand the ...
Connor P. Dolan   +3 more
doaj   +1 more source

Development and characterization of an intra‐articular fracture mediated model of post‐traumatic osteoarthritis

open access: yesJournal of Experimental Orthopaedics, 2023
Purpose This study aimed to develop and characterize a closed intra‐articular fracture (IAF) mediated post‐traumatic osteoarthritis (PTOA) model in rats to serve as a testbed for putative disease modifying interventions. Methods Male rats were subject to
Michael S. Valerio   +7 more
doaj   +1 more source

Epidemiology and Risk of Amputation in Patients With Diabetes Mellitus and Peripheral Artery Disease

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2020
Peripheral artery disease (PAD) stems from atherosclerosis of lower extremity arteries with resultant arterial narrowing or occlusion. The most severe form of PAD is termed chronic limb-threatening ischemia and carries a significant risk of limb loss and
M. Creager   +4 more
semanticscholar   +1 more source

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