Results 31 to 40 of about 104,877 (268)

Predictors for Amputation in Patients with Diabetic Foot Wound

Vascular Specialist International, 2018
Purpose: Diabetic foot wound (DFW) is known as a major contributor of nontraumatic lower extremity amputation. We aimed to evaluate overall amputation rates and risk factors for amputation in patients with DFW. Materials and Methods: From January 2014
Se-Young Kim, Tae Hoon Kim, Jun-Young Choi, Yu-Jin Kwon, Dong Hui Choi, Ki Chun Kim, Min Ji Kim, Ho Kyung Hwang, Kyung-Bok Lee   +8 more
doaj   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

In-vivo evaluation of vitamin E loaded muscle void fillers for the provisional treatment of volumetric muscle loss

BMC Research Notes
Objective This study investigates the therapeutic potential of α-tocopherol (Vitamin E, VitE), delivered locally via a polyethylene glycol (PEG) hydrogel serving as a muscle void filler (MVF), for the acute treatment of volumetric muscle loss (VML) in a ...
Michael S. Valerio, Andrew R. Clark, Marissa N. Behun, Christopher L. Dearth, Stephen M. Goldman   +4 more
doaj   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

A Two-Stage Approach Integrating Provisional Biomaterial-Mediated Stabilization Followed by a Definitive Treatment for Managing Volumetric Muscle Loss Injuries

Journal of Functional Biomaterials
Treatment of volumetric muscle loss (VML) faces challenges due to its unique pathobiology and lower priority in severe musculoskeletal injury management.
Andrew R. Clark, Jonathan Kulwatno, Sergey S. Kanovka, George J. Klarmann, Claudia E. Hernandez, Roman M. Natoli, Todd O. McKinley, Benjamin K. Potter, Christopher L. Dearth, Stephen M. Goldman   +9 more
doaj   +1 more source

A Novel Perfused Full‐Thickness Human Skin Microphysiological System for Modeling Injury, Regeneration, Tumor Pathophysiology, and Therapeutics Development

Advanced Healthcare Materials, EarlyView.
What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu, Hamid Malekzadeh, Alexa Rivera Del Rio Hernandez, Naresh Mahajan, Ethan Banks, Dayyan Ur Rahman, José A. Arellano, Katherine S. Yang, Alexey Altman, G.V. Naveen Kumar, Matthew L. Steinhauser, Jeffrey A. Gusenoff, J. Peter Rubin, Asim Ejaz   +13 more
wiley   +1 more source

The musculotendinous interface: insights into development, injury, and recovery for military medical applications

Frontiers in Physiology
Musculoskeletal injuries (MSKIs) are a major cause of morbidity and lost duty time for military service members, impacting overall military readiness, with overuse injuries being particularly prevalent among them. Musculotendinous injuries, affecting the
Alex T. Adams, Alex T. Adams, Zachary G. Davis, Zachary G. Davis, Kyle F. Browder, Kyle F. Browder, Christopher L. Dearth, Christopher L. Dearth, Stephen M. Goldman, Stephen M. Goldman   +9 more
doaj   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

Comparing the mechanical energetics of walking among individuals with unilateral transfemoral limb loss using socket and osseointegrated prosthetic interfaces

Scientific Reports
Osseointegration (OI), or bone-anchoring, of a prosthesis is a transformative procedure for addressing issues of socket fit among individuals with lower limb loss. Mechanically, the removal of the socket interface substantially alters the transmission of
Pawel R. Golyski, Benjamin K. Potter, Jonathan A. Forsberg, Brad D. Hendershot   +3 more
doaj   +1 more source

Characterization of initial ankle-foot prosthesis prescription patterns in U.S. Service members following unilateral transtibial amputation

Frontiers in Rehabilitation Sciences, 2023
IntroductionThe purpose of this study was to explore relationships between patient-specific characteristics and initial ankle-foot prosthesis prescription patterns among U.S.
Patrick G. Monaghan, Ashley D. Knight, Ashley D. Knight, Ashley D. Knight, Sarah A. Brinkerhoff, Kenneth D. Harrison, Christopher L. Dearth, Christopher L. Dearth, Brad D. Hendershot, Brad D. Hendershot, Brad D. Hendershot, JoEllen M. Sefton, Michael Zabala, Adan Vazquez, Adan Vazquez, David Shannon, David Crumbley, Jaimie A. Roper   +17 more
doaj   +1 more source