Results 51 to 60 of about 216,547 (314)

A Soft Robotic Device for Targeted Massage Therapy of Residual Limbs

Advanced Robotics Research, EarlyView.
Residual limb edema after amputation can hinder recovery and delay prosthetic fitting. This study presents a soft‐robotic wearable device that delivers sequential compression through pneumatic McKibben actuators. By replicating the principles of manual lymphatic drainage, the device generates controlled mechanotherapeutic pressure patterns, providing a
Maria Grazia Polizzotto, Alessio Capecchi, Maartje Van der Lingen, Emanuele Gruppioni, Arianna Menciassi, Linda Paternò   +5 more
wiley   +1 more source

In-vivo evaluation of vitamin E loaded muscle void fillers for the provisional treatment of volumetric muscle loss

BMC Research Notes
Objective This study investigates the therapeutic potential of α-tocopherol (Vitamin E, VitE), delivered locally via a polyethylene glycol (PEG) hydrogel serving as a muscle void filler (MVF), for the acute treatment of volumetric muscle loss (VML) in a ...
Michael S. Valerio, Andrew R. Clark, Marissa N. Behun, Christopher L. Dearth, Stephen M. Goldman   +4 more
doaj   +1 more source

Validity of Mangled Extremity Score System to Predict Limb Salvage on Cases of Traumatic Popliteal Artery Injuries: A Case Series and Review of the Literature

Journal of Endovascular Resuscitation and Trauma Management, 2023
Background: Popliteal artery injuries carry a risk of amputation rate ranging from 9.7% to 28%. The mangled extremity score system (MESS) was originally authenticated in only 26 patients and it was concluded that an MESS ≥ 7 equated to a 100% rate of ...
Amr Abdelghaffar Hanfy Mahmoud, Mohamed AbdelSamie Khalek Elbahat   +1 more
doaj   +1 more source

Phantom pain [PDF]

, 2016
Almost anyone with a limb amputation experiences phantom sensations. Moreover, the majority of amputees experience pain. This phenomenon is known as ‘Phantom pain’ and is described as the pain felt from a body part, usually a limb, which is no longer ...
Duca, Kristina, Muscat, Richard
core  

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

The musculotendinous interface: insights into development, injury, and recovery for military medical applications

Frontiers in Physiology
Musculoskeletal injuries (MSKIs) are a major cause of morbidity and lost duty time for military service members, impacting overall military readiness, with overuse injuries being particularly prevalent among them. Musculotendinous injuries, affecting the
Alex T. Adams, Alex T. Adams, Zachary G. Davis, Zachary G. Davis, Kyle F. Browder, Kyle F. Browder, Christopher L. Dearth, Christopher L. Dearth, Stephen M. Goldman, Stephen M. Goldman   +9 more
doaj   +1 more source

Risk Factors for Lower Extremity Amputation in Diabetic Foot Ulcer Patients: A Case-Control Study

Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga, 2020
Introduction: Diabetes mellitus is a metabolic syndrome that is marked by higher blood glucose. The uncontrolled high blood glucose can lead to complication, such as diabetic foot.
Gusti Agung Ayu Ira Kencana Dewi, Sony Wibisono, I Putu Alit Pawana   +2 more
doaj   +1 more source

Early redox activities modulate Xenopus tail regeneration. [PDF]

, 2018
Redox state sustained by reactive oxygen species (ROS) is crucial for regeneration; however, the interplay between oxygen (O2), ROS and hypoxia-inducible factors (HIF) remains elusive.
Ferreira, Fernando, Luxardi, Guillaume, Raghunathan, VijayKrishna, Zhao, Min, Zhu, Kan   +4 more
core   +2 more sources

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

A Two-Stage Approach Integrating Provisional Biomaterial-Mediated Stabilization Followed by a Definitive Treatment for Managing Volumetric Muscle Loss Injuries

Journal of Functional Biomaterials
Treatment of volumetric muscle loss (VML) faces challenges due to its unique pathobiology and lower priority in severe musculoskeletal injury management.
Andrew R. Clark, Jonathan Kulwatno, Sergey S. Kanovka, George J. Klarmann, Claudia E. Hernandez, Roman M. Natoli, Todd O. McKinley, Benjamin K. Potter, Christopher L. Dearth, Stephen M. Goldman   +9 more
doaj   +1 more source