Results 101 to 110 of about 2,302,069 (327)

Metabolic changes during cardiac regeneration in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background The axolotl is a prominent model organism of heart regeneration due to its ability to anatomically and functionally repair the heart after an injury that mimics human myocardial infarction. In humans, such an injury leads to permanent scarring. Cardiac regeneration has been linked to metabolism and the oxygenation state, but so far,
Anita Dittrich, Sofie Amalie Andersson, Morten Busk, Kasper Hansen, Casper Bindzus Foldager, Johan Palmfeldt, Asger Andersen, Michael Pedersen, Mikkel Vendelbo, Kirstine Lykke Nielsen, Henrik Lauridsen   +10 more
wiley   +1 more source

Intratumoral chemotherapy in an integumentary squamous cell carcinoma in a cockatiel (Nymphicus hollandicus) [PDF]

, 2018
An eight-year-old, female cockatiel (Nymphicus hollandicus) was presented with anorexia, lethargy, a mass at the lower side of the wing and discoloration of the feathers.
Antonissen, Gunther, Croubels, Siska, Ducatelle, Richard, Garmyn, An, Hellebuyck, Tom, Martel, An, Van de Maele, Isabel, Van Hecke, Naomi   +7 more
core  

The endocannabinoid system regulates both ependymoglial and neuronal cell responses to a tail amputation in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino, Sarah E. Walker, Gaynor E. Spencer, Robert Carlone   +3 more
wiley   +1 more source

Empagliflozin after myocardial infarction with or without diabetes and chronic kidney disease: Insights from EMPACT‐MI

ESC Heart Failure, EarlyView.
Impact of empagliflozin in patients with and without T2D or CKD in the EMPACT‐MI trial. Baseline characteristics, HF outcomes and subgroup analysis of efficacy endpoints are shown. # Hazard ratios estimated via Cox proportional hazard model (unless indicated otherwise). ^ Rate ratios via negative binomial regression.
Francesco Fioretti, Javed Butler, Jacob A. Udell, W. Schuyler Jones, Mark C. Petrie, Josephine Harrington, Michaela Mattheus, Johann Bauersachs, Antoni Bayes‐Genis, Shaun G. Goodman, Tomasz Gasior, James L. Januzzi, Renato D. Lopes, Piotr Ponikowski, Xavier Rossello, Morten Schou, Peter van der Meer, Dragos Vinereanu, Shelley Zieroth, Martina Brueckmann, Mikhail Sumin, Deepak L. Bhatt, Adrian F. Hernandez, Stefan D. Anker   +23 more
wiley   +1 more source

Should Every Mummified Toe Be Amputated? Toe Preservation With a Perforator Flap

Plastic and Reconstructive Surgery, Global Open
Background:. Peripheral gangrene, caused by various etiologies, including diabetes, peripheral artery disease, trauma, and vasopressor use, poses significant challenges. Traditional management often involves proximal amputation, which carries a high risk
Bo Young Park, MD, PhD
doaj   +1 more source

Osseointegrated prostheses for rehabilitation following amputation : The pioneering Swedish model. [PDF]

, 2017
The direct attachment of osseointegrated (OI) prostheses to the skeleton avoids the inherent problems of socket suspension. It also provides physiological weight bearing, improved range of motion in the proximal joint, as well as osseoperceptive sensory ...
Brånemark, Rickard, Li, Yan
core   +1 more source

Digital implementation strategy to increase SGLT2 inhibitor uptake in heart failure: Study design of EMAIL‐HF

ESC Heart Failure, EarlyView.
Abstract Aims The EMAIL‐HF trial aims to evaluate whether a digital guideline implementation strategy can increase and accelerate initiation of sodium‐glucose co‐transporter 2 (SGLT2) inhibitors in patients with heart failure (HF). Methods and results EMAIL‐HF is a pragmatic, registry‐based, randomized controlled trial including patients with a ...
Mariam Elmegaard, Lars Køber, Mads Kristian Ersbøll, Theis Lange, Christian Ditlev Tuxen, Mette Rauhe Mouridsen, Trine Kiilerich Lauridsen, Jens Jakob Thune, Peter Godsk Jørgensen, Morten Lamberts, Nadia Paarup Dridi, Peter Bonfils, Morten Petersen, Nis Ottesen Stride, Anders Barasa, Jesper Jensen, Caroline Garred, Emil Fosbøl, Emil Wolsk, John McMurray, Mark Petrie, Morten Schou   +21 more
wiley   +1 more source

Evaluation of the Surgical and Pharmacological Treatment of Diabetic Foot Infection: A Retrospective Study [PDF]

, 2017
BACKGROUND: Diabetic foot infection is a major cause of patient disabilities and lowers limb amputations, with high treatment costs and hospitalisation requirements.
Aliakbar, Adil Hassan, Alsaadi, Malath Azeez, Barrak, Abbas Abd Zaid   +2 more
core   +4 more sources

Peptide RL‐QN15 Regulates Functions of Epidermal Stem Cells to Accelerate Skin Wound Regeneration via the FZD8/β‐Catenin Axis

Exploration, EarlyView.
Amphibian‐derived peptide RL‐QN15 activates the Wnt/β‐catenin signaling pathway by interacting with the FZD8 membrane receptor, promoting epidermal stem cells proliferation, migration, stemness, and EMT processes, thus promoting skin wound healing.
Yuansheng Li, Qiuye Jia, Naixin Liu, Saige Yin, Junyuan Wang, Yujing Ding, Yuliu Yang, Ying Peng, Zeqiong Ru, Shaoyang Zhang, Bu'er Qi, Jun Sun, Li He, Ying Wang, Kun Guo, Xinwang Yang   +15 more
wiley   +1 more source

Impact of delayed amputation on clinical outcomes compared to that of early amputation in patients with blunt polytrauma

Scientific Reports
Delayed amputation after failed limb salvage can lead to negative clinical and functional outcomes due to complications, including re-amputation.
Jinjoo Kim, Wanseon Choi, Wontae Cho, Jonghwan Moon   +3 more
doaj   +1 more source