Results 1 to 10 of about 134,783 (203)

Negative CT Contrast Agents for the Diagnosis of Malignant Osteosarcoma

Advanced Science, 2019
The current positive computed tomography (CT) contrast agents (PCTCAs) including clinical iodides, present high CT density value (CT‐DV). However, they are incapable for the accurate diagnosis of some diseases with high CT‐DV, such as osteosarcoma ...
Wenbo Bu, Baoming Wang
exaly   +2 more sources

Osteosarcoma of Jaw Masquerading as Calcifying Epithelial Odontogenic Tumour- A Diagnostic Dilemma [PDF]

Journal of Clinical and Diagnostic Research, 2022
Osteogenic osteosarcoma is the most widely recognised primary malignant bone tumour involving particularly the appendicular skeleton. Osteosarcoma of jaw including maxillary and mandibular osteosarcoma accounts for about 7% of cases.
Neha Sethi, Nimisha Devpura, Nitin Khutenta, ML Yadav, Maneesh Vijaywargia   +4 more
doaj   +1 more source

Osteosarcoma [PDF]

Journal of Bone and Mineral Research, 2010
Abstract It has been difficult to identify the molecular features central to the pathogenesis of osteosarcoma owing to a lack of understanding of the cell or origin, the absence of identifiable precursor lesions, and its marked genetic complexity at the time of presentation.
Richard, Gorlick, Chand, Khanna
openaire   +4 more sources

The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway

Acta Pharmaceutica Sinica B, 2022
Osteosarcoma is a kind of bone tumor with highly proliferative and invasive properties, a high incidence of pulmonary metastasis and a poor prognosis. Chemotherapy is the mainstay of treatment for osteosarcoma.
Geni Ye, Maohua Huang, Yong Li, Jie Ouyang, Minfeng Chen, Qing Wen, Xiaobo Li, Huhu Zeng, Pei Long, Zepei Fan, Junqiang Yin, Wencai Ye, Dongmei Zhang   +12 more
doaj   +1 more source

Long Intergenic Noncoding RNA00265 Enhances Cell Viability and Metastasis via Targeting miR-485-5p/USP22 Axis in Osteosarcoma

Frontiers in Oncology, 2022
Osteosarcoma is one of the bone malignancies in children and adolescents. Long noncoding RNAs (lncRNAs) have been demonstrated to participate in osteosarcoma development and progression.
Ting Chen, Jinxin Liu, He Zhang, Jiatong Li, Guanning Shang   +4 more
doaj   +1 more source

The bioinformatic approach identifies PARM1 as a new potential prognostic factor in osteosarcoma

Frontiers in Oncology, 2023
ObjectiveTo explore the key factors affecting the prognosis of osteosarcoma patients.MethodsBased on the GEO dataset and differential expression analysis of normal and osteosarcoma tissues, the gene modules related to the prognosis of osteosarcoma ...
Haijun Feng, Liping Wang, Jie Liu, Shengbao Wang   +3 more
doaj   +1 more source

Aberrant Expression of PAFAH1B3 Affects Proliferation and Apoptosis in Osteosarcoma

Frontiers in Oncology, 2021
Osteosarcoma is a major malignant tumor of bone and soft tissue, which is presenting with early metastasis and a high mortality rate. Platelet activating factor acetylhydrolase 1B3 (PAFAH1B3), a cancer-relevant molecular, was found to play a vital role ...
Jian Fan, Yi Yang, Ji-kui Qian, Xin Zhang, Jia-qing Ji, Li Zhang, Shan-zhu Li, Feng Yuan   +7 more
doaj   +1 more source

PKIB involved in the metastasis and survival of osteosarcoma

Frontiers in Oncology, 2022
Osteosarcoma is frequently metastasized at the time of diagnosis in patients. However, the underlying mechanism of osteosarcoma metastasis remains poorly understood.
Rongxue Wan, Rongxue Wan, Gu Yang, Qianzhen Liu, Xiaokang Fu, Zengping Liu, Huilai Miao, Huilai Miao, Huan Liu, Huan Liu, Wenhua Huang, Wenhua Huang, Wenhua Huang   +12 more
doaj   +1 more source

Integrated multiomic analysis and high‐throughput screening reveal potential gene targets and synergetic drug combinations for osteosarcoma therapy

MedComm, 2023
Although great advances have been made over the past decades, therapeutics for osteosarcoma are quite limited. We performed long‐read RNA sequencing and tandem mass tag (TMT)‐based quantitative proteome on osteosarcoma and the adjacent normal tissues ...
Wenchao Zhang, Lin Qi, Zhongyue Liu, Shasha He, Cheng‐zhi Wang, Ying Wu, Lianbin Han, Zhenxin Liu, Zheng Fu, Chao Tu, Zhihong Li   +10 more
doaj   +1 more source

The Role of NR4A1 in the Pathophysiology of Osteosarcoma: A Comprehensive Bioinformatics Analysis of the Single-Cell RNA Sequencing Dataset

Frontiers in Oncology, 2022
Osteosarcoma is a kind of aggressive human malignancy, and the prognosis of the patients with osteosarcoma remains low. Studies have demonstrated that the tumor microenvironment plays a key role in regulating osteosarcoma progression. Recent studies have
Weidong Liu, Yuedong Hao, Xiao Tian, Jing Jiang, Quanhe Qiu   +4 more
doaj   +1 more source