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Osteosarcoma [PDF]

open access: yesNature Reviews Disease Primers, 2022
Osteosarcoma is the most common primary malignant tumour of the bone. Osteosarcoma incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in males.
Janeway, Katherine   +9 more
core   +9 more sources

The etiology of osteosarcoma

open access: yes, 2009
Studies to determine the etiology of osteosarcoma involve epidemiologic and environmental factors and genetic impairments. Factors related to patient characteristics include age, gender, ethnicity, growth and height, genetic and familial factors, and ...
Giulia Ottaviani   +3 more
core   +3 more sources

The epidemiology of osteosarcoma

open access: yes, 2009
Osteosarcoma derives from primitive bone-forming mesenchymal cells and is the most common primary bone malignancy. The incidence rates and 95% confidence intervals of osteosarcoma for all races and both sexes are 4.0 (3.5-4.6) for the range 0-14 years ...
Giulia Ottaviani   +3 more
core   +4 more sources

Negative CT Contrast Agents for the Diagnosis of Malignant Osteosarcoma

open access: yesAdvanced Science, 2019
The current positive computed tomography (CT) contrast agents (PCTCAs) including clinical iodides, present high CT density value (CT‐DV). However, they are incapable for the accurate diagnosis of some diseases with high CT‐DV, such as osteosarcoma ...
Xianfu Meng, Baoming Wang, Yanyan Liu
exaly   +2 more sources

Osteosarcoma of Jaw Masquerading as Calcifying Epithelial Odontogenic Tumour- A Diagnostic Dilemma [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
Osteogenic osteosarcoma is the most widely recognised primary malignant bone tumour involving particularly the appendicular skeleton. Osteosarcoma of jaw including maxillary and mandibular osteosarcoma accounts for about 7% of cases.
Neha Sethi   +4 more
doaj   +1 more source

The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway

open access: yesActa Pharmaceutica Sinica B, 2022
Osteosarcoma is a kind of bone tumor with highly proliferative and invasive properties, a high incidence of pulmonary metastasis and a poor prognosis. Chemotherapy is the mainstay of treatment for osteosarcoma.
Geni Ye   +12 more
doaj   +1 more source

Long Intergenic Noncoding RNA00265 Enhances Cell Viability and Metastasis via Targeting miR-485-5p/USP22 Axis in Osteosarcoma

open access: yesFrontiers in Oncology, 2022
Osteosarcoma is one of the bone malignancies in children and adolescents. Long noncoding RNAs (lncRNAs) have been demonstrated to participate in osteosarcoma development and progression.
Ting Chen   +4 more
doaj   +1 more source

The bioinformatic approach identifies PARM1 as a new potential prognostic factor in osteosarcoma

open access: yesFrontiers in Oncology, 2023
ObjectiveTo explore the key factors affecting the prognosis of osteosarcoma patients.MethodsBased on the GEO dataset and differential expression analysis of normal and osteosarcoma tissues, the gene modules related to the prognosis of osteosarcoma ...
Haijun Feng   +3 more
doaj   +1 more source

Osteosarcoma [PDF]

open access: yesAnnals of Oncology, 2010
The successful treatment of patients with osteosarcoma requires close cooperation within an experienced multidisciplinary team including pediatric or medical oncologists, surgeons, pathologists and radiologists. Therefore, therapy should be performed in specialized centers able to provide access to the full spectrum of care.
J, Ritter, S S, Bielack
openaire   +4 more sources

Aberrant Expression of PAFAH1B3 Affects Proliferation and Apoptosis in Osteosarcoma

open access: yesFrontiers in Oncology, 2021
Osteosarcoma is a major malignant tumor of bone and soft tissue, which is presenting with early metastasis and a high mortality rate. Platelet activating factor acetylhydrolase 1B3 (PAFAH1B3), a cancer-relevant molecular, was found to play a vital role ...
Jian Fan   +7 more
doaj   +1 more source

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