Results 21 to 30 of about 126,889 (304)

A Rare Cause of Shoulder Pain: Osteosarcoma of the Scapula [PDF]

open access: yes, 2021
Osteosarcoma is a malignant bone tumor usually seen in adolescent and early adulthood and often with long bones; patients complain of pain and swelling. Plain radiography revealed cortex destruction and moth-eaten style medullary lesions. Reported herein
Ayşe Dicle Turhanoğlu, Kadir Güler
core   +1 more source

MiR-138 Acts as a Tumor Suppressor by Targeting EZH2 and Enhances Cisplatin-Induced Apoptosis in Osteosarcoma Cells. [PDF]

open access: yesPLoS ONE, 2016
Chemotherapeutic insensitivity remains a major obstacle to treating osteosarcoma effectively. Recently, increasing evidence has suggested that microRNAs (miRNAs) are involved in drug resistance. However, the effect of miR-138 on cisplatin chemoresistance
Ziqiang Zhu   +5 more
doaj   +1 more source

lncRNA MELTF-AS1 facilitates osteosarcoma metastasis by modulating MMP14 expression

open access: yesMolecular Therapy: Nucleic Acids, 2021
Osteosarcoma is a highly aggressive cancer common in children and adolescents. There is still a lack of effective treatments for metastatic or recurrent osteosarcoma.
Lei Ding   +9 more
doaj   +1 more source

OSTEOSARCOMA IN THE PEDIATRIC AGE [PDF]

open access: yes, 2018
Osteosarcoma is the most common form of malignant bone tumor; it is characterized by malignant mesenchymal cells producing osteoid or immature bone. The tumor predominantly involves children, teenagers and young adults with a peak of incidence in the ...
Francesco Roberto Evola
core   +1 more source

Decreased expression of miR-195 mediated by hypermethylation promotes osteosarcoma

open access: yesOpen Medicine, 2022
Osteosarcoma (OS) is the most common type of primary malignant bone tumor. The early lung metastasis of osteosarcoma is one of the main factors of poor prognosis.
Sun Tianhao   +6 more
doaj   +1 more source

Cullin-1 Regulates MG63 Cell Proliferation and Metastasis and is a Novel Prognostic Marker of Osteosarcoma

open access: yesThe International Journal of Biological Markers, 2017
Background There is no reliable marker available for early detection, diagnostic confirmation or disease prognosis of osteosarcoma. Cullin-1 (CUL1) is a newly reported tumor-related gene, and we aimed to unravel its role in osteosarcoma.
Qinghua Cheng, Guoyong Yin
doaj   +1 more source

Long noncoding RNA OR3A4 promotes the proliferation and invasion of osteosarcoma cells by sponging miR-1227-5p

open access: yesJournal of Bone Oncology, 2020
Background: Long noncoding RNAs (lncRNAs) have been identified as key players in promoting tumourigenesis in osteosarcoma. LncRNA OR3A4 (OR3A4) has been reported as an oncogene in a number of tumours.
Changcheng Yang   +8 more
doaj   +1 more source

Advances in Osteosarcoma

open access: yesCurrent Osteoporosis Reports, 2023
Abstract Purpose of Review This article gives a brief overview of the most recent developments in osteosarcoma treatment, including targeting of signaling pathways, immune checkpoint inhibitors, drug delivery strategies as single or combined approaches, and the identification of new therapeutic targets to face this ...
Panez-Toro, I.   +6 more
openaire   +4 more sources

Circulating exosomes secreted by osteosarcoma cells are potential biomarkers for metastasis [PDF]

open access: yes, 2021
Selva, Erica M.Sampson, ValerieOsteosarcoma is a primary malignant bone tumor found in children and is the third most common cancer in children and adolescents.
Jeshurin, Madeline
core   +1 more source

Analysis of the genetic predisposition of patients with osteosarcoma or Ewing's sarcoma to other pathologies [PDF]

open access: yes, 2023
reservedLa tesi è volta a studiare e analizzare le mutazioni genetiche di pazienti con osteosarcoma o sarcoma di Ewing per comprendere se i soggetti dello studio siano geneticamente predisposti ad altre patologie.
BIANCHIN, CARLOTTA
core  

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