Results 11 to 20 of about 126,514 (307)

PKIB involved in the metastasis and survival of osteosarcoma

Frontiers in Oncology, 2022
Osteosarcoma is frequently metastasized at the time of diagnosis in patients. However, the underlying mechanism of osteosarcoma metastasis remains poorly understood.
Rongxue Wan, Rongxue Wan, Gu Yang, Qianzhen Liu, Xiaokang Fu, Zengping Liu, Huilai Miao, Huilai Miao, Huan Liu, Huan Liu, Wenhua Huang, Wenhua Huang, Wenhua Huang   +12 more
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Integrated multiomic analysis and high‐throughput screening reveal potential gene targets and synergetic drug combinations for osteosarcoma therapy

MedComm, 2023
Although great advances have been made over the past decades, therapeutics for osteosarcoma are quite limited. We performed long‐read RNA sequencing and tandem mass tag (TMT)‐based quantitative proteome on osteosarcoma and the adjacent normal tissues ...
Wenchao Zhang, Lin Qi, Zhongyue Liu, Shasha He, Cheng‐zhi Wang, Ying Wu, Lianbin Han, Zhenxin Liu, Zheng Fu, Chao Tu, Zhihong Li   +10 more
doaj   +1 more source

SOX12 Promotes Stem Cell-Like Phenotypes and Osteosarcoma Tumor Growth by Upregulating JAGGED1

Stem Cells International, 2021
SOX12 plays a role in promoting the growth of some tumors; however, its role in osteosarcoma remains unclear. From gene expression omnibus (GEO) and tumor alterations relevant for genomics-driven therapy (TARGET) databases, Kaplan–Meier analyses were ...
Weifei Zhang, Fei Yu, Jian Weng, Yien Zheng, Jianjing Lin, Tiantian Qi, Yihao Wei, Deli Wang, Hui Zeng   +8 more
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AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis in osteosarcoma

Signal Transduction and Targeted Therapy, 2021
Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents. Although activator of HSP90 ATPase activity 1 (AHA1) is reported to be a potential oncogene, its role in osteosarcoma progression remains largely unclear ...
Diwei Zheng, Weihai Liu, Wenlin Xie, Guanyu Huang, Qiwei Jiang, Yang Yang, Jiarong Huang, Zihao Xing, Mengling Yuan, Mengning Wei, Yao Li, Junqiang Yin, Jingnan Shen, Zhi Shi   +13 more
doaj   +1 more source

The Role of NR4A1 in the Pathophysiology of Osteosarcoma: A Comprehensive Bioinformatics Analysis of the Single-Cell RNA Sequencing Dataset

Frontiers in Oncology, 2022
Osteosarcoma is a kind of aggressive human malignancy, and the prognosis of the patients with osteosarcoma remains low. Studies have demonstrated that the tumor microenvironment plays a key role in regulating osteosarcoma progression. Recent studies have
Weidong Liu, Yuedong Hao, Xiao Tian, Jing Jiang, Quanhe Qiu   +4 more
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TMED3/RPS15A Axis promotes the development and progression of osteosarcoma

Cancer Cell International, 2021
Background Osteosarcoma is a primary malignant tumor that mainly affects children and young adults. Transmembrane emp24 trafficking protein 3 (TMED3) may be involved in the regulation of malignant cancer behaviors.
Wei Xu, Yifan Li, Xiaojian Ye, Yunhan Ji, Yu Chen, Xiangyang Zhang, Zhikun Li   +6 more
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miR-26a Reverses Multidrug Resistance in Osteosarcoma by Targeting MCL1

Frontiers in Cell and Developmental Biology, 2021
The multidrug resistance (MDR) acquired in human osteosarcoma is a huge obstacle for effective chemotherapy. Recently, microRNA-26a (miR-26a) has been associated with the pathogenesis and progression of osteosarcoma.
Ming Li, Wei Ma
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CEMIP Promotes Osteosarcoma Progression and Metastasis Through Activating Notch Signaling Pathway

Frontiers in Oncology, 2022
Cell migration inducing protein (CEMIP) has been linked to carcinogenesis in several types of cancers. However, the role and mechanism of CEMIP in osteosarcoma remain unclear. This study investigated the role of CEMIP in the progression and metastasis of
Jun Cheng, Yan Zhang, Yan Zhang, Rongjun Wan, Jun Zhou, Xin Wu, Qizhi Fan, Jingpeng He, Wei Tan, Youwen Deng   +9 more
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lncRNA MELTF-AS1 facilitates osteosarcoma metastasis by modulating MMP14 expression

Molecular Therapy: Nucleic Acids, 2021
Osteosarcoma is a highly aggressive cancer common in children and adolescents. There is still a lack of effective treatments for metastatic or recurrent osteosarcoma.
Lei Ding, Taiyuan Liu, Yuan Qu, Zhichen Kang, Lixin Guo, Haina Zhang, Junjie Jiang, Fuling Qu, Wanbao Ge, Shanyong Zhang   +9 more
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Maxillary osteosarcoma in a beef suckler cow [PDF]

, 2012
A ten-year-old beef suckler cow was referred to the Scottish Centre for Production Animal Health and Food Safety of the University of Glasgow, because of facial swelling in the region of the right maxilla.
Prins, D.G.J., Wittek, Thomas, Diether G J Prins, Wittek, T., Prins, Diether G. J., Barrsett David C, Barrett, David C., Barrett, D.C., Wittek Thomas, Prins Diether G J, Thomas Wittek, David C Barrett   +11 more
core   +1 more source