Results 41 to 50 of about 134,783 (203)

OSTEOSARCOMA IN THE PEDIATRIC AGE

, 2018
Osteosarcoma is the most common form of malignant bone tumor; it is characterized by malignant mesenchymal cells producing osteoid or immature bone. The tumor predominantly involves children, teenagers and young adults with a peak of incidence in the ...
Francesco Roberto Evola
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A Rare Cause of Shoulder Pain: Osteosarcoma of the Scapula

, 2021
Osteosarcoma is a malignant bone tumor usually seen in adolescent and early adulthood and often with long bones; patients complain of pain and swelling. Plain radiography revealed cortex destruction and moth-eaten style medullary lesions. Reported herein
Ayşe Dicle Turhanoğlu, Kadir Güler
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3D Printed Multifunctional PEEK Bone Scaffold for Multimodal Treatment of Osteosarcoma and Osteomyelitis [PDF]

, 2021
In this work, we developed the first 3D PEEK based bone scaffold with multi-functions targeting challenging bone diseases such as osteosarcoma and osteomyelitis.
Zhongyang, Lin, Meixuan, Du, Miaomiao, He, dan, Sun, Li, Zhang, Ce, zhu, Leizhen, Huang, Yubao, Li, Jingcheng, Wang, Limin, Liu, Juehan, Wang, Yueming, Song, Ganjun, Feng, Yong, Huang   +13 more
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CT45A1 promotes the metastasis of osteosarcoma cells in vitro and in vivo through β-catenin

Cell Death and Disease, 2021
Increased expression of cancer/testis antigens (CTAs) is reported in various tumors. However, the unique role of CTAs in tumor genesis has not yet been verified.
Mingxin Wen, Hui Ren, Shouqiang Zhang, Tao Li, Jiefeng Zhang, Peng Ren   +5 more
doaj   +1 more source

The Genetics of Osteosarcoma [PDF]

Sarcoma, 2012
Osteosarcoma is a primary bone malignancy with a particularly high incidence rate in children and adolescents relative to other age groups. The etiology of this often aggressive cancer is currently unknown, because complicated structural and numeric genomic rearrangements in cancer cells preclude understanding of tumour development.
Martin, Jeff W., Squire, Jeremy A., Zielenska, Maria   +2 more
openaire   +2 more sources

Osteosarcoma associated with diamond-blackfan anaemia: a case of a child receiving growth hormone therapy [PDF]

, 2004
Purpose: Diamond–Blackfan anaemia (DBA) is a rare pure congenital red cell aplasia, usually presenting in infancy or early childhood. The literature suggests a predisposition to haemopoietic malignancy but in addition solid tumours have been reported ...
Briggs, TW, Pringle, J, Lee, RS, Higgs, D, Haddo, O   +4 more
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circCAMSAP1 promotes osteosarcoma progression and metastasis by sponging miR-145-5p and regulating FLI1 expression

Molecular Therapy: Nucleic Acids, 2021
Osteosarcoma is the most common primary malignant bone tumor in adolescents. While chemotherapy combined with surgery can improve the prognosis of some patients, chemo-resistance is still a huge obstacle in osteosarcoma treatment.
Zizheng Chen, Wenbin Xu, Deguang Zhang, Junjie Chu, Shuying Shen, Yan Ma, Qingxin Wang, Gang Liu, Teng Yao, Yizhen Huang, Huali Ye, Jiying Wang, Jianjun Ma, Shunwu Fan   +13 more
doaj   +1 more source

Analysis of the genetic predisposition of patients with osteosarcoma or Ewing's sarcoma to other pathologies

, 2023
reservedLa tesi è volta a studiare e analizzare le mutazioni genetiche di pazienti con osteosarcoma o sarcoma di Ewing per comprendere se i soggetti dello studio siano geneticamente predisposti ad altre patologie.
BIANCHIN, CARLOTTA
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The phosphatase CTDSPL2 promotes proliferation, invasion, metastasis and regorafenib resistance in osteosarcoma

Journal of Bone Oncology
Osteosarcoma is the most common bone malignancy in children and adolescents. Patients with metastatic and recurrent osteosarcoma have poor prognosis.
Guannan Bai, Shaobo Zhao, Manli Zhao, Limiao Chen, Wenhao Chen   +4 more
doaj   +1 more source

PiRNA hsa_pir_018849 promotes the proliferation and invasion of osteosarcoma cells by regulating the stability of CCN5 mRNA

Journal of Orthopaedic Surgery and Research
Background Osteosarcoma is a primary malignant bone tumor and that is predominantly found in adolescents and young adults, and it often occurs during periods of rapid bone growth.
Jiale Huang, Saishuai Yang, Peng Liu, He Jiang, Zhiming Cui, Jiajia Chen   +5 more
doaj   +1 more source