Results 61 to 70 of about 134,783 (203)

Fibroblastic growth factor receptor 1 amplification in osteosarcoma is associated with poor response to neo-adjuvant chemotherapy. [PDF]

, 2014
Osteosarcoma, the most common primary bone sarcoma, is a genetically complex disease with no widely accepted biomarker to allow stratification of patients for treatment.
M. Fernanda Amary, Behjati, S., Ye, H., Berisha, F, Strauss, S.J., Lehovsky, K., Campbell, P.J., Frezza, A.M., Presneau, Nadège, Pillay, N., Fernanda Amary, M., Bhavisha Khatri, Tarpey, P, Tarpey, P., Pillay, N, Adrienne M. Flanagan, Sam Behjati, Fernanda Amary, M, Tirabosco, R, Patrick Tarpey, Tirabosco, R., Peter J. Campbell, Roberto Tirabosco, Presneau, N, Nischalan Pillay, Khatri, B., Georgina Forbes, Frezza, AM, Flanagan, AM, Fitim Berisha, Anna M. Frezza, Campbell, PJ, Nadège Presneau, Strauss, SJ, Lehovsky, K, Khatri, B, Forbes, G., Sandra J. Strauss, Forbes, G, Behjati, S, Hongtao Ye, Berisha, F., Flanagan, A.M., Ye, H, Katie Lehovsky   +44 more
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βig-h3 promotes human osteosarcoma cells metastasis by interacting with integrin α2β1 and activating PI3K signaling pathway.

PLoS ONE, 2014
Osteosarcoma, the most common primary bone tumor in children and young adolescents, is characterized by local invasion and distant metastasis. But the detailed mechanisms of osteosarcoma metastasis are not well known.
Yun-Shan Guo, Rui Zhao, Jie Ma, Wei Cui, Zhen Sun, Bo Gao, Shu He, Yue-Hu Han, Jing Fan, Liu Yang, Juan Tang, Zhuo-Jing Luo   +11 more
doaj   +1 more source

The role of eukaryotic initiation factor 4E (eIF4E) in osteosarcoma metastasis [PDF]

, 2011
The most significant problem for cancer patients is the dissemination of cancer cells and the formation of metastatic disease. Emblematic of the problem is the clinical progression seen in most patients with osteosarcoma, where metastasis to the lung is ...
Osborne, Tanasa S.
core  

HSP90AA1-mediated autophagy promotes drug resistance in osteosarcoma

Journal of Experimental & Clinical Cancer Research, 2018
Background Osteosarcoma is the most common primary bone tumor in children and adolescents. Unfortunately, osteosarcoma treatments often fail due to the development of chemoresistance, of which the underlying molecular mechanisms still remain unclear.
Xin Xiao, Wei Wang, Yuqian Li, Di Yang, Xiaokang Li, Chao Shen, Yan Liu, Xianzhu Ke, Shuo Guo, Zheng Guo   +9 more
doaj   +1 more source

Characterization of human osteosarcoma cell lines : Comparison of phenotypes of cells established from primary and metastatic lung lesions [PDF]

, 1995
P(論文)Osteosarcoma is a highly invasive malignant neoplasm which may metastasize to distant sites, particularly the lung. Two osteosarcoma cell lines were established from osteosarcoma tissue obtained from the proximal end of a right tibial tumor, "KIKU ...
越智, 眞理, 24423
core  

Osteosarcoma [PDF]

, 2019
This book is titled Osteosarcoma - Diagnosis, Mechanisms, and Translational Developments, and focuses on recent advancements and novel ideas in osteosarcoma research.

core   +1 more source

Screening drugs of Anemoside B4 for MFAP4 expression in osteosarcoma in PDTX to increase personalized medicine

Discover Oncology
Osteosarcoma is a group of malignant tumors with a variety of histological subtypes and biological characteristics. This type of tumor mainly affects bones and soft tissues and is commonly found in children and young people.
Lei Zhang, Lijuan Zeng, Jing Zhang, Zhiwei He, Xiaozhou Liu   +4 more
doaj   +1 more source

Telangiectatic Osteosarcoma: Ultrastrucural and Immunohistochemical observations

, 1996
Telangiectatic Osteosarcoma: Ultrastrucural and Immunohistochemical ...
COMIN C. E., CAPANNA, RODOLFO, SANTUCCI M., CALDORA P., FRANCHI, ALESSANDRO, CAMPANACCI D. A.   +5 more
core  

SERPINH1 enhances the malignancy of osteosarcoma via PI3K-Akt signaling pathway

Translational Oncology
Background: Serpin Family H Member 1 (SERPINH1) may be involved in the regulation of occurrence and development of tumors. However, the role and mechanism of SERPINH1 in osteosarcoma remain poorly understood.
Kezhou Xia, Xinghan Huang, Yingchun Zhao, Isabelle Yang, Weichun Guo   +4 more
doaj   +1 more source

ONZIN Upregulation by Mutant p53 Contributes to Osteosarcoma Metastasis Through the CXCL5-MAPK Signaling Pathway

Cellular Physiology and Biochemistry, 2018
Background/Aims: Gain-of-function of mutant p53 is associated with a high rate of lung metastasis in osteosarcoma. To investigate the mechanism of mutant p53-induced osteosarcoma metastasis, expression array analysis was performed, comparing non ...
Yanqin Zhang, Qianghua Hu, Guixin Li, Lili Li, Shoulei Liang, Yun Zhang, Jiayong Liu, Zhengfu Fan, Lin Li, Bingzheng Zhou, Yongxin Ruan, Xueli Yang, She’an Chen, Tianyang  Mu, Guowen Wang, Shunbin Xiong   +15 more
doaj   +1 more source