Results 81 to 90 of about 171,941 (345)

Real-World Achievement of Guideline-Concordant Treatment and Survival in Osteosarcoma: A Nationwide Registry Study. [PDF]

Cancer Sci
A nationwide registry analysis showed that real‐world achievement of guideline‐concordant treatment was high across Japan and associated with superior survival in osteosarcoma patients. Older age and trunk tumor location were associated with lower rates of achievement of guideline‐concordant treatment, largely reflecting treatment feasibility.
Fujiwara T, Kawai A, Ozaki T.
europepmc   +2 more sources

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

SERPINH1 enhances the malignancy of osteosarcoma via PI3K-Akt signaling pathway

Translational Oncology
Background: Serpin Family H Member 1 (SERPINH1) may be involved in the regulation of occurrence and development of tumors. However, the role and mechanism of SERPINH1 in osteosarcoma remain poorly understood.
Kezhou Xia, Xinghan Huang, Yingchun Zhao, Isabelle Yang, Weichun Guo   +4 more
doaj   +1 more source

Telangiectatic Osteosarcoma: Ultrastrucural and Immunohistochemical observations

, 1996
Telangiectatic Osteosarcoma: Ultrastrucural and Immunohistochemical ...
COMIN C. E., CAPANNA, RODOLFO, SANTUCCI M., CALDORA P., FRANCHI, ALESSANDRO, CAMPANACCI D. A.   +5 more
core  

Osteosarcoma

, 2021
Osteosarcoma is the most common type of cancer that starts in bones. I will be researching and presenting on the visual differences between healthy bone tissue and bone tissue that has been affected by osteosarcoma as well as symptoms and preventative ...
Retz, Andrew
core  

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

ONZIN Upregulation by Mutant p53 Contributes to Osteosarcoma Metastasis Through the CXCL5-MAPK Signaling Pathway

Cellular Physiology and Biochemistry, 2018
Background/Aims: Gain-of-function of mutant p53 is associated with a high rate of lung metastasis in osteosarcoma. To investigate the mechanism of mutant p53-induced osteosarcoma metastasis, expression array analysis was performed, comparing non ...
Yanqin Zhang, Qianghua Hu, Guixin Li, Lili Li, Shoulei Liang, Yun Zhang, Jiayong Liu, Zhengfu Fan, Lin Li, Bingzheng Zhou, Yongxin Ruan, Xueli Yang, She’an Chen, Tianyang  Mu, Guowen Wang, Shunbin Xiong   +15 more
doaj   +1 more source

Osteosarcoma costal [PDF]

, 1944
I El Prof. Luque presenta la historia clínica, con dos ilustraciones, de un joven con un tumor localizado en la región intervértebro-escapular derecha.
Luque, Manuel José, Manuel José Luque
core  

Resveratrol Loaded by Folate-Modified Liposomes Inhibits Osteosarcoma Growth and Lung Metastasis via Regulating JAK2/STAT3 Pathway

, 2023
Wen Ting Zhu,1,* Xiang Feng Zeng,2,* Hua Yang,2 Meng Lei Jia,1 Wei Zhang,2 Wei Liu,2 Sheng Yao Liu3 1Department of Pharmacy, Biomedicine Research Center, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, The Third Affiliated ...
Yang H, Zhang W, Liu SY, Zhu WT, Jia ML, Zeng XF, Liu W   +6 more
core  

Circulating exosomes secreted by osteosarcoma cells are potential biomarkers for metastasis

, 2021
Selva, Erica M.Sampson, ValerieOsteosarcoma is a primary malignant bone tumor found in children and is the third most common cancer in children and adolescents.
Jeshurin, Madeline
core   +1 more source