Archives of Pathology & Laboratory Medicine, 2014 Parosteal osteosarcoma is a rare malignant bone tumor arising from the bone cortical surface. It most commonly occurs in young women over the metaphyseal region, especially the long bones near the knee joint. Patients usually report a slow-growing mass for years.
Jen-Fan, Hang, Paul Chih-Hsueh, Chen
openaire +2 more sources
Don't cancel the surgery just yet! A case report of positive preoperative pregnancy test due to a soft tissue sarcoma production of ectopic beta human chorionic gonadotropin. [PDF]
, 2018 Soft tissue sarcomas are a rare group of mesenchymal malignancies which can range from low to high grade. These tumors have different clinical, radiographic, and histopathological characteristics. Beta human chorionic gonadotropin is a naturally secreted
Blank, Alan Todd +3 more
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FUS-CHOP promotes invasion in myxoid liposarcoma through a SRC/FAK/RHO/ROCK-dependent pathway [PDF]
, 2017 Deregulated SRC/FAK signaling leads to enhanced migration and invasion in many types of tumors. In myxoid and round cell liposarcoma (MRCLS), an adipocytic tumor characterized by the expression of the fusion oncogene FUS-CHOP, SRC have been found as one ...
González, M. Victoria +3 more
core +2 more sources
Current Therapeutic Strategies and Novel Approaches in Osteosarcoma [PDF]
, 2013 Osteosarcoma is the most frequent malignant primary bone tumor and a main cause of cancer-related death in children and adolescents. Although long-term survival in localized osteosarcoma has improved to about 60% during the 1960s and 1970s, long-term ...
Allison +74 more
core +2 more sources
Immunotherapy of osteosarcoma based on immune microenvironment modulation
Frontiers in ImmunologyOsteosarcoma is a highly malignant tumor with unsatisfactory therapeutic outcomes achieved by chemotherapy, radiotherapy, and surgery. As an emerging oncological treatment, immunotherapy has shown potential in the clinical management of many tumors but ...
Heping Lian +8 more
doaj +1 more source
Artificial Cells, Nanomedicine, and Biotechnology, 2019 Purpose The function of lncRNAs in cancer stem cells (CSCs) remains to be elucidated. The present study aimed to investigate the regulating role of a novel lncRNA, hypoxia-inducible factor-2α (HIF-2α) promoter upstream transcript (HIF2PUT), in ...
Ding Zhao +3 more
doaj +1 more source
Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design. [PDF]
, 2019 Accelerating cures for children with cancer remains an immediate challenge as a result of extensive oncogenic heterogeneity between and within histologies, distinct molecular mechanisms evolving between diagnosis and relapsed disease, and limited ...
Baxter, Patricia +68 more
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Negative CT Contrast Agents for the Diagnosis of Malignant Osteosarcoma
Advanced Science, 2019 The current positive computed tomography (CT) contrast agents (PCTCAs) including clinical iodides, present high CT density value (CT‐DV). However, they are incapable for the accurate diagnosis of some diseases with high CT‐DV, such as osteosarcoma ...
Xianfu Meng +9 more
doaj +1 more source
Study on the relationship between livin expression and osteosarcoma
Journal of Bone Oncology, 2018 Objective: The aim of this meta-analysis was to analysis the expression of livin in human osteosarcoma. Methods: We searched the Pubmed, Science Direct, Embase and Web of Science, CNKI, Wanfang and VIP for relevant original studies.
Meng Du +5 more
doaj +1 more source
Emerging Translational Opportunities in Comparative Oncology With Companion Canine Cancers: Radiation Oncology. [PDF]
, 2019 It is estimated that more than 6 million pet dogs are diagnosed with cancer annually in the USA. Both primary care and specialist veterinarians are frequently called upon to provide clinical care that improves the quality and/or quantity of life for ...
Boss, Mary-Keara +2 more
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