Results 31 to 40 of about 126,514 (307)

LncRNA EBLN3P attributes methotrexate resistance in osteosarcoma cells through miR-200a-3p/O-GlcNAc transferase pathway

open access: yesJournal of Orthopaedic Surgery and Research, 2022
Background Osteosarcoma is highly malignant. The migration, invasion, and chemoresistance contribute to poor prognosis of osteosarcoma. Research reported that endogenous bornavirus-like nucleoprotein 3 pseudogene (EBLN3P) promotes the progression of ...
Ming-Xia Sun   +4 more
doaj   +1 more source

Cellular functions and molecular mechanisms of ubiquitination in osteosarcoma

open access: yesFrontiers in Oncology, 2022
Although some advances have been made in the treatment of osteosarcoma in recent years, surgical resection remains the mainstream treatment. Initial and early diagnosis of osteosarcoma could be very difficult to achieve due to the insufficient ...
Jiaxun Song   +8 more
doaj   +1 more source

Indoleamine 2,3- Dioxygenase: A Novel Immunotherapeutic Target for Osteosarcoma

open access: yes, 2022
Introduction: Tumour-emitted molecules induce immunosuppression in the tumour microenvironment. An immunosuppressive enzyme, indoleamine 2,3-dioxygenase (IDO/IDO1), facilitates immune escape in several malignant tumours, including osteosarcoma ...
Farooq, Asim   +2 more
core   +1 more source

A Novel Approach to Anti-Cancer Therapy in Osteosarcoma

open access: yes, 2021
In this paper I have sought to outline the molecular pathogenesis of osteosarcoma with some reference to potential therapeutic targets currently under investigation.The genetic basis of osteosarcoma has also been presented and discussed, along with the ...
Kunlere, Michael Ayodeji
core  

A Rare Cause of Shoulder Pain: Osteosarcoma of the Scapula

open access: yes, 2021
Osteosarcoma is a malignant bone tumor usually seen in adolescent and early adulthood and often with long bones; patients complain of pain and swelling. Plain radiography revealed cortex destruction and moth-eaten style medullary lesions. Reported herein
Ayşe Dicle Turhanoğlu, Kadir Güler
core   +1 more source

Osteosarcomas of the Heart [PDF]

open access: yesThe American Journal of Surgical Pathology, 1991
We reviewed nine primary cardiac sarcomas with osteosarcomatous differentiation. The patients' ages ranged from 24 to 67 (mean 38 years). All tumors were surgical specimens from the left atrium; many were clinically diagnosed as atypical myxomas. In eight cases complete excisions were attempted, one requiring reconstruction with grafting; one tumor was
Burke, Allen P., Virmani, Renu
openaire   +3 more sources

CT45A1 promotes the metastasis of osteosarcoma cells in vitro and in vivo through β-catenin

open access: yesCell Death and Disease, 2021
Increased expression of cancer/testis antigens (CTAs) is reported in various tumors. However, the unique role of CTAs in tumor genesis has not yet been verified.
Mingxin Wen   +5 more
doaj   +1 more source

GIANT CELL-RICH OSTEOSARCOMA : A CASE REPORT [PDF]

open access: yes, 1996
1996-12-27This report discusses a rare case of giant cell-rich osteosarcoma. The patient, a 19-year-old male, was diagnosed with a metadiaphyseal osteolytic lesion when he consulted a local doctor complaining of motion pain without swelling.
NAGASAKA, TETSURO   +5 more
core   +1 more source

Telangiectatic Osteosarcoma [PDF]

open access: yesJournal of Orthopaedic Surgery, 2013
Purpose. To review records of 8 patients with telangiectatic osteosarcoma (TOS) and determine whether pathologic fractures correlate with recurrence and survival. Methods.
Jordi Colomina   +3 more
openaire   +4 more sources

Interleukin-24 inhibits the phenotype and tumorigenicity of cancer stem cell in osteosarcoma via downregulation Notch and Wnt/β-catenin signaling

open access: yesJournal of Bone Oncology, 2021
Osteosarcoma frequently presents as recurrence and metastasis, even if the primary lesion was eradicated and/or radiotherapy and chemotherapy were administered.
Baobiao Zhuo   +6 more
doaj   +1 more source

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