Results 191 to 200 of about 53,951 (246)

3D Printing of Bacteriophage‐Loaded Hydrogels: Development of a Local and Long‐Lasting Delivery System

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
This research investigates the feasibility of 3D‐printing of a bacteriophage‐containing hydrogel made of alginate and methylcellulose. The printed hydrogels steadily release active bacteriophages for up to 35 days which is beneficial to treat implant‐associated infections.
Corina Vater, Gopala Krishna Mannala, Max von Witzleben, Richard Frank Richter, Nike Walter, Michael Gelinsky, Volker Alt, Anja Lode, Markus Rupp   +8 more
wiley   +1 more source

Negative Pressure Wound Therapy in the Treatment of Complicated Wounds of the Foot and Lower Limb in Diabetic Patients: A Retrospective Case Series. [PDF]

J Clin Med
Mihalache O, Simion L, Doran H, Bîrligea AB, Luca DC, Chitoran E, Bobircă F, Mustățea P, Pătrașcu T.   +8 more
europepmc   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Clinical Severity and Systemic Inflammatory Indices as Predictors of In-Hospital Mortality After Limb Amputation a Retrospective Cohort Study. [PDF]

J Clin Med
Namitokov A, Bakhishev T, Vinogradov R, Zakeryaev A, Butaev S, Urakov E, Khangereev G, Sakhno L, Pchegatluk M, Ignatenko D.   +9 more
europepmc   +1 more source

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed   +22 more
wiley   +1 more source

Negative pressure wound therapy for combat-related extremity vascular injuries: clinical experience from the war in Ukraine. [PDF]

Scand J Trauma Resusc Emerg Med
Sivash II, Koval BM.
europepmc   +1 more source

Surgical Repair of a Partial Penile Amputation From a Hair Tourniquet Under Local Anesthesia. [PDF]

Cureus
Midenberg E, Anele UA.
europepmc   +1 more source

Radical surgical treatment of calcaneal osteomyelitis: clinical characteristics and treatment efficacy based on a synthesis analysis of 364 reported cases. [PDF]

J Orthop Surg Res
Liu ZX, Chen P, Qiu LL, Zheng XL, Yu B, Jiang N.   +5 more
europepmc   +1 more source

The Use of Calcium Sulphate as a Drug Delivery System in Lower Limb Amputation. [PDF]

Cureus
Morris G, Kattimani R, Fisher N.
europepmc   +1 more source

Educational impact of a cost-efficient porcine model for toe amputation simulation training: Enhancing amputation education. [PDF]

JPRAS Open
Mahmood A, Kiew CYK, Shah A, Singh R, Abuarqoub M, Barnes L, Wordsworth M.   +6 more
europepmc   +1 more source