Results 171 to 180 of about 56,868 (264)

In Defence of Oblique Intention

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract Recent work on lying has revived an old action‐theoretic category: oblique, or indirect, intention. I argue that some liars intend deception obliquely. Sneddon objects that this category is drastic and unjustified: it counts all foreseen side‐effects as intended. My response is that oblique intention is not mere foresight.
Vladimir Krstić
wiley   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

open access: yesThe FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati   +4 more
wiley   +1 more source

The Impact of Periodontal Health Interventions on the Risk of Ischemic Stroke: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Aim To systematically review the evidence on the relationship between periodontal health interventions and the risk of first‐ever ischemic stroke. Materials and Methods Search strategy included electronic and hand searching to January 2025. MEDLINE (OVID), EMBASE (OVID), SCOPUS, LILACS, Web of Science (WOS) and Cochrane Central Register of ...
Jorge Moldes   +7 more
wiley   +1 more source

Pre‐implementation safety evaluation of an AI decision‐support system for surgical antimicrobial prophylaxis

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Large language models (LLMs) show potential to support antimicrobial prescribing but require simulation‐based, institution‐specific safety evaluation prior to any consideration of clinical use. In Australia, antimicrobial prescribing represents a high‐risk domain for digital decision‐support systems due to patient safety and ...
Joshua Andrews   +4 more
wiley   +1 more source

Management of Periodontal Abscesses and Endodontic‐Periodontal Lesions—A Systematic Review

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To evaluate the management of periodontal abscesses and endodontic‐periodontal lesions (EPLs). Methods Seven focused questions addressed outcomes such as pocket depth (PD), bleeding on probing (BOP), tooth loss or ovoid elevation. The literature search covered three electronic databases and manual sources for intervention studies.
Henrik Dommisch   +5 more
wiley   +1 more source

USP30 inhibits wound healing in diabetic foot ulcers by promoting TRAF6‐induced ferroptosis and angiogenesis inhibition

open access: yesJournal of Diabetes Investigation, EarlyView.
High glucose upregulates USP30 in HUVECs, which deubiquitinates and stabilizes TRAF6. Stabilized TRAF6 suppresses GPX4 and SLC7A11, increases ROS/MDA/lipid peroxidation, and activates ferroptosis and apoptosis, leading to impaired angiogenesis and delayed wound healing.
Jingjing Yuan   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy