Results 171 to 180 of about 1,068,619 (283)

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

The FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati, Chandra Sekhar Yadavalli, Md Monirul Hoque, Swapna Thota, Gadiparthi N. Rao   +4 more
wiley   +1 more source

Striving for Consensus: Neuroma Prevention and Preferred Approaches in Surgical Digit Amputations-A Survey of Hand Surgeons. [PDF]

J Clin Med
Draschl A, Girsch W, Kamolz LP, Sadoghi P, Dolderer J, Hoh M, Nischwitz SP.   +6 more
europepmc   +1 more source

The Impact of Periodontal Health Interventions on the Risk of Ischemic Stroke: A Systematic Review and Meta‐Analysis

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Aim To systematically review the evidence on the relationship between periodontal health interventions and the risk of first‐ever ischemic stroke. Materials and Methods Search strategy included electronic and hand searching to January 2025. MEDLINE (OVID), EMBASE (OVID), SCOPUS, LILACS, Web of Science (WOS) and Cochrane Central Register of ...
Jorge Moldes, Joao Botelho, Manuel Rodríguez‐Yáñez, Vanessa Machado, Juan Blanco, Tomás Sobrino, Rogelio Leira, Yago Leira   +7 more
wiley   +1 more source

Initial surgical management of injuries to the upper extremities for patients with multiple and/or severe injuries - a systematic review and clinical practice guideline update. [PDF]

Eur J Trauma Emerg Surg
Berk T, Könsgen N, Lechler P, Imach S, Schär M, Bieler D, Horst K, Hildebrand F, Goossen K.   +8 more
europepmc   +1 more source

Two‐Year Outcome of Partial Pulpotomy Using Mineral Trioxide Aggregate or a Premixed Calcium Silicate Cement: A Randomized Clinical Trial

International Endodontic Journal, EarlyView.
ABSTRACT Aim To compare the clinical and radiographic outcomes of partial pulpotomy performed with mineral trioxide aggregate (White MTA Angelus) or a premixed calcium silicate‐based putty cement (NeoPutty) in mature mandibular molars with deep carious lesions and to explore factors associated with treatment outcome.
Alberto Serrano, Emmanuel João Nogueira Leal Silva, Henry F. Duncan, Antonio Jesús Conde Villar, Gaizka Loroño, Roberto Estévez, Claudia Brizuela, Ruth Pérez Alfayate   +7 more
wiley   +1 more source

Utility of TcPO₂ in Assessing Microcirculatory Improvement and Minimizing Amputation Levels for Hemodialysis Access-Induced Distal Ischemia: A Case Report. [PDF]

Yonago Acta Med
Ikuta K, Suyama Y, Umeda R, Ohga M, Fumita K, Kuroda M, Endo M, Kishimoto Y, Yagi S.   +8 more
europepmc   +1 more source

Management of Periodontal Abscesses and Endodontic‐Periodontal Lesions—A Systematic Review

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To evaluate the management of periodontal abscesses and endodontic‐periodontal lesions (EPLs). Methods Seven focused questions addressed outcomes such as pocket depth (PD), bleeding on probing (BOP), tooth loss or ovoid elevation. The literature search covered three electronic databases and manual sources for intervention studies.
Henrik Dommisch, Daniela Hoedke, Marina Dourou, Elena Calciolari, David Herrera, Selena Toma   +5 more
wiley   +1 more source

Hyperbaric Oxygen Therapy for Diabetic Lower-Limb Wounds in the Caribbean: A Retrospective Cohort Study. [PDF]

Int Wound J
Chingan Martino V, Pusel M, Bouamama D, Gibert D, Cheret A.   +4 more
europepmc   +1 more source

USP30 inhibits wound healing in diabetic foot ulcers by promoting TRAF6‐induced ferroptosis and angiogenesis inhibition

Journal of Diabetes Investigation, EarlyView.
High glucose upregulates USP30 in HUVECs, which deubiquitinates and stabilizes TRAF6. Stabilized TRAF6 suppresses GPX4 and SLC7A11, increases ROS/MDA/lipid peroxidation, and activates ferroptosis and apoptosis, leading to impaired angiogenesis and delayed wound healing.
Jingjing Yuan, Shuang Sui, Zhenghua Yang, Kaiwen Zhang, Qiang Hu   +4 more
wiley   +1 more source