Results 191 to 200 of about 1,068,619 (283)

A randomized phase 2 trial of socrodeucitinib in moderate‐to‐severe plaque psoriasis

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
In moderate‐to‐severe plaque psoriasis, socrodeucitinib (6 mg/12 mg) significantly outperformed placebo at week 12: PASI 75 response rates 28.6%/72.1% vs. 7.5%. Meanwhile, socrodeucitinib illustrated a favourable safety and tolerability profile, warranting further study.
Ling Han   +24 more
wiley   +1 more source

Perioperative Transfusion Trigger Score Versus Restrictive Transfusion in Older Non‐Cardiac Surgery Patients: A Multicenter Randomized Controlled Trial

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Restrictive transfusion (Hb < 7 g/dL) is recommended for most perioperative patients, but the optimal threshold for those with cardiovascular disease or Hb 7–10 g/dL remains uncertain. The Perioperative Transfusion Trigger Score (POTTS), which integrates adrenaline requirement, FiO2, temperature, and angina history, may standardize ...
Shucong Liang   +9 more
wiley   +1 more source

Togetherness in Couples Living With Chronic Obstructive Pulmonary Disease: An Interpretive Interview Study

open access: yesJournal of Clinical Nursing, EarlyView.
ABSTRACT Aim To explore how persons with chronic obstructive pulmonary disease (COPD) and partners experience illness‐related changes in shared everyday life and intimacy, and how these changes affect well‐being. Design An interpretive phenomenological interview study.
Louise Muxoll Gronhaug   +4 more
wiley   +1 more source

Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin

open access: yesJournal of Periodontal Research, EarlyView.
This review highlights the 30 years of evolution of APCs, with a focus on their clinical applications and recent technological advancements. ABSTRACT Nearly three decades have now passed since autologous platelet concentrates (APCs) were introduced into clinical practice.
Richard J. Miron   +7 more
wiley   +1 more source

The incidence of vaccine‐associated sarcomas in cats: a systematic review and meta‐analysis

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives Feline injection‐site sarcoma is a rare but serious adverse event associated with vaccination in cats. Published estimates of feline injection‐site sarcoma incidence vary widely, contributing to uncertainty in clinical decision‐making and incidence communication.
F. Emdin   +5 more
wiley   +1 more source

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