Results 41 to 50 of about 87,457 (293)

Surgical Treatment of Post-Amputation Foot Deformations in Diabetic Neuropathy

open access: yesНеотложная медицинская помощь
Relevance The number of amputations performed on patients with diabetic foot syndrome is increasing all over the world. Almost half of these operations are the so-called “minor amputations” carried out within the foot.
P. S. Bardyugov   +2 more
doaj   +1 more source

Results of treatment of diabetic patients with chronic critical ischemia of the lower limb

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2018
Background. In Ukraine, the current shortage of qualified vascular surgical care, especially for diabetic people, remains relevant. The diabetic patients with chronic critical ischemia of the lower limb often undergo unreasonable conservative treatment ...
S.N. Didenko
doaj   +1 more source

Diabetic Hand Infections: Factors at Presentation Influencing Amputation and Number of Surgical Procedures

open access: yesIndian Journal of Plastic Surgery, 2021
Background Diabetic hand infections are associated with significant morbidity and disability. Amputations cause permanent disability, and multiple surgical procedures lead to morbidity.
Sanjai Ramkumar   +5 more
doaj   +1 more source

Transableism, Disability and Paternalism in Public Health Ethics: Taxonomies, identity Disorders and Persistent Unexplained Physical Symptoms [PDF]

open access: yes, 2006
Transableism is a term which refers to moving between states of being able and disabled by choice rather than by happenstance. Insofar as this may imply a choice to become dependent, claims upon the healthcare system are likely to result.
Cox, Stephen, Mackenzie, Robin
core   +1 more source

Bioelectronic Sensors for Neuromuscular Perception in Human‐Machine Interfaces

open access: yesAdvanced Robotics Research, EarlyView.
This review summarizes recent advances in bioelectronic sensors for neuromuscular perception in human‐machine interfaces. By integrating biopotential, electrical impedance, and electrochemical sensing strategies with flexible electrode interfaces, these bioelectronic sensing systems enable intuitive, real‐time detection of muscle and nerve activity ...
Junwei Li   +5 more
wiley   +1 more source

PIEZO1‐GPX4 Axis Mediates Mechanical Stress‐Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation

open access: yesAdvanced Science, EarlyView.
Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen   +14 more
wiley   +1 more source

Sleep Deprivation Activates a Conserved Lactate‐H3K18la‐RORα Axis Driving Neutrophilic Inflammation Across Species

open access: yesAdvanced Science, EarlyView.
Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou   +15 more
wiley   +1 more source

Staged salvage of diabetic foot with Chopart amputation and intramedullary nailing

open access: yesSAGE Open Medical Case Reports, 2021
We present a stepwise surgical approach that can be used, in lieu of a transtibial amputation, to preserve the lower limb in the setting of severe diabetic foot infections.
Alexandre Leme Godoy-Santos   +5 more
doaj   +1 more source

Dermatological Malignancies at a University Teaching Hospital in north-western Tanzania: A Retrospective Review of 154 Cases [PDF]

open access: yes, 2012
Dermatological malignancies are among the most common form of cancers and the global incidence has been increasing at an alarming rate. A retrospective study was conducted to determine the prevalence, histopathological pattern, anatomical distribution ...
Chalya, Phillipo L.   +6 more
core   +2 more sources

POSTN‐Mediated Interplay of M1 Polarized Macrophage with Tendon‐Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?

open access: yesAdvanced Science, EarlyView.
The mechanism diagram reveals that the formation of trauma‐induced heterotopic ossification (HO) is accompanied by the polarization of macrophages toward the M1 phenotype. Additionally, the extracellular vesicles secreted by M1 macrophages, which contain periostin (POSTN), directly bind to PTK7 in tendon‐derived stem cells (TDSCs).
Hang Liu   +9 more
wiley   +1 more source

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