Results 231 to 240 of about 736,868 (299)

Experimental induction of myelin damage in post-mortem human brain slice cultures. [PDF]

Acta Neuropathol Commun
Meijns NRC, Muñoz González G, Stolker S, T Hart B, Plug BC, Bugiani M, Grootemaat A, van der Wel N, Bilir Ö, Roya-Kouchaki K, Teo W, K Stys P, Hill S, Schenk GJ, Kooij G, Newland B, Luchicchi A.   +16 more
europepmc   +1 more source

Toward Objective Anal Cancer Screening: From Swab‐Based Genome‐Wide Methylation Marker Discovery to Novel Test Development

International Journal of Cancer, EarlyView.
ABSTRACT Anal high‐grade squamous intraepithelial lesions (HSIL:AIN2/3) are precursors to anal cancer, and early detection and treatment through screening is crucial for effective cancer prevention. Current guidelines recommend anal swab‐based screening and highlight the need for objective biomarkers to improve risk stratification.
Kirsten Rozemeijer, Jürgen Claesen, Fernando Dias Gonçalves Lima, Albertus T. Hesselink, Phoebe Klingers, Timo ter Braak, Yara van den Burgt, Chris J. L. M. Meijer, Jan M. Prins, Henry J. C. de Vries, Mark A. van de Wiel, Renske D. M. Steenbergen   +11 more
wiley   +1 more source

Urinary and Faecal Amino‐Acids as Biomarkers for Colorectal Neoplasia in Lynch Syndrome—A Prospective Longitudinal Study

International Journal of Cancer, EarlyView.
ABSTRACT In Lynch syndrome, colonoscopy surveillance for colorectal cancer (CRC) is burdensome and post‐colonoscopy CRCs still occur. Unlike the faecal immunochemical test (FIT), gut metabolomic alterations including amino‐acids have shown potential as non‐invasive biomarkers for detecting both advanced and non‐advanced sporadic colorectal neoplasia ...
Roza C. M. Opperman, Elsa L. S. A. van Liere, Animesh Acharjee, Sudip Mondal, Eduard A. Struys, Andreas Antoniadis, Jasmijn E. B. de Boer, Shivra R. Siriram, Abdellatif Bakkali, Sofie Bosch, Maarten A. J. M. Jacobs, Jan Jacob Koornstra, Johan P. Kuijvenhoven, Monique E. van Leerdam, Manon C. W. Spaander, Tim G. J. de Meij, Evelien Dekker, Dewkoemar Ramsoekh, Nanne K. H. de Boer   +18 more
wiley   +1 more source

Transmission of Anellovirus From Kidney-Donor to Pediatric Recipient: An Exploratory Study. [PDF]

Pediatr Transplant
Klomp LS, Burggraaff MGJM, Bakker M, Molier M, Timmerman AL, Deijs M, Feltkamp M, van der Hoek L, Bouts AHM.   +8 more
europepmc   +1 more source

Early Cessation of Adjuvant Anti‐PD‐1 Therapy in Stage III and IV Melanoma

International Journal of Cancer, EarlyView.
ABSTRACT One year of adjuvant anti‐PD‐1 has improved disease‐free survival in Stage III melanoma. It is unknown whether shorter treatment duration affects outcomes. Real‐world data may help clarify this. In this retrospective observational study, patients with resected Stage III/IV melanoma receiving adjuvant anti‐PD‐1 in the Netherlands from 2018 to ...
Manja Bloem, Melissa M. de Meza, Cato D. M. Boreel, Maureen J. B. Aarts, Franchette W. P. J. van den Berkmortel, Christian U. Blank, Willeke A. M. Blokx, Marye J. Boers‐Sonderen, Han J. Bonenkamp, Jan Willem B. de Groot, John B. Haanen, Geke A. P. Hospers, Ellen Kapiteijn, Djura Piersma, Bart Rikhof, Lieke H. J. Simkens, Marion A. Stevense‐den Boer, Astrid A. M. van der Veldt, Karijn P. M. Suijkerbuijk, Alfonsus J. M. van den Eertwegh, Michel W. J. M. Wouters   +20 more
wiley   +1 more source

Cell-free DNA genomic and fragmentomic features for early outcome prediction in large B cell lymphoma. [PDF]

Cell Rep Med
Wang S, Mapar P, Moldovan N, van der Pol Y, Safrastyan A, van Werkhoven E, Tantyo NA, Snieder B, Do Brito Valente AF, de Jonge AV, Dinmohamed A, Drees EEE, Roemer MGM, Ylstra B, Klerk CPW, Strobbe L, Sandberg Y, Boersma RS, Koene H, Pruijt H, de Heer K, van Rijn R, Bilgin YM, de Jongh E, Nijland M, van der Poel M, Koster A, Nieuwenhuizen L, Fijnheer R, Beeker A, Mous R, Vergote VKJ, Vermaat JSP, Pegtel DM, Chamuleau MED, Mouliere F.   +35 more
europepmc   +1 more source

Stock Price Deviations From Fundamentals Levels: Mis‐Valuation due to Investor Overconfidence?

International Journal of Finance &Economics, EarlyView.
ABSTRACT We use the Residual Income Valuation Model to obtain fundamental values for sample stocks in six Eurozone markets. We then estimate the deviation between the fundamental values and actual stock prices. Subsequently, we examine whether these deviations can be systematically explained by business cycle trends, trends in local economic sentiment,
Stella N. Spilioti, Andrianos E. Tsekrekos   +1 more
wiley   +1 more source

Near real-time multi-class segmentation for intravascular optical coherence tomography using knowledge distillation. [PDF]

Eur Heart J Digit Health
van der Waerden RGA, Volleberg RHJA, Cancian P, van der Zande JL, Luttikholt TJ, Gu X, Heil L, Mol JQ, Nishimiya K, Roleder T, Sánchez CI, van Ginneken B, Thannhauser J, van Royen N, Išgum I, Saitta S.   +15 more
europepmc   +1 more source

Cost‐effectiveness of a randomized controlled trial comparing low‐dose aspirin to placebo for the prevention of recurrent preterm birth

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 399-407, April 2025.
Abstract To assess the cost‐effectiveness of low‐dose aspirin compared to placebo for the prevention of recurrent preterm birth from a healthcare perspective. This was a cost‐effectiveness analysis alongside a multicenter, randomized, double‐blinded, placebo‐controlled trial.
Anadeijda J. E. M. C. Landman, Hana M. Broulikova, Laura Visser, Tobias A. J. Nijman, Marieke A. C. Hemels, Karin C. Vollebregt, Elisabeth M. A. Boormans, Henk A. Bremer, Esther Tuinman, Josje Langenveld, Flip van der Made, Robbert J. P. Rijnders, Huib A. A. M. van Vliet, Liv M. Freeman, Roel de Heus, Judith Blaauw, Ineke Krabbendam, Rafli van de Laar, Marieke F. G. Verberg, Hubertina C. J. Scheepers, Ben W. Mol, Christianne J. M. de Groot, Martijn A. Oudijk, Judith E. Bosmans, Marjon A. de Boer   +24 more
wiley   +1 more source

Matters arising: bridging predictive algorithms and clinical practice in DBS contact selection. [PDF]

NPJ Parkinsons Dis
van der Weide A, Wiggerts Y, Hubers D, Keulen BJ, de Neeling MGJ, Stam MJ, van Wijk BCM, Bot M, Schuurman R, de Bie RMA, Beudel M.   +10 more
europepmc   +1 more source