Results 41 to 50 of about 378,475 (338)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Prevalence and risk factors for carriage of ESBL-producing Enterobacteriaceae in Amsterdam

open access: yesJournal of Antimicrobial Chemotherapy, 2016
Objectives The objectives of this study were to determine the prevalence of carriage of ESBL-producing Enterobacteriaceae (ESBL-E) in a representative sample of the general adult Dutch community, to identify risk factors and to gain understanding of the ...
E. A. Reuland   +7 more
semanticscholar   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

A three-dimensional statistical shape model of the growing mandible

open access: yesScientific Reports, 2021
Mandibular growth and morphology are important topics in the field of oral and maxillofacial surgery. For diagnostic and planning purposes, a normative database or statistical shape model of the growing mandible can be of great benefit.
C. Klop, MAGIC Amsterdam
doaj   +1 more source

Climate Change Preparedness: Comparing Future Urban Growth and Flood Risk in Amsterdam and Houston.

open access: yesSustainability, 2019
Rising sea levels and coastal population growth will increase flood risk of more people and assets if land use changes are not planned adequately.
Youjung Kim, Galen D. Newman
semanticscholar   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Middle‐Class Versus Working‐Class White Mothers’ Approaches to Diversity in the Netherlands

open access: yesSocial Inclusion
There is a large body of literature on how white middle‐class parents select schools for their children in gentrifying urban contexts. In this study, we aimed to explore the experiences of such parents after enrolling their children in ethnically mixed ...
Elif Keskiner   +5 more
doaj   +1 more source

Leer el Corán en la comunidad sefardí de Amsterdam en el siglo XVII

open access: yesAl-Qantara : Revista de Estudios Arabes, 2014
Este trabajo presenta una traducción del Corán al castellano, desconocida hasta ahora, conservada en la Ets Haim/Biblioteca Montezinos de la comunidad judío-portuguesa de Amsterdam.
Harm den Boer, Pier Mattia Tommasino
doaj   +1 more source

A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Loss‐of‐function mutations in the scaffold subunit of protein phosphatase 2A (PP2A), PPP2R1A, sensitize ovarian clear cell carcinoma to immune checkpoint blockade (ICB) by enhancing the interferon gamma response and promoting antitumor immune cell infiltration.
Matheus Henrique Dias, René Bernards
wiley   +1 more source

Estimating the potential to prevent locally acquired HIV infections in a UNAIDS Fast-Track City, Amsterdam

open access: yeseLife, 2022
Background: More than 300 cities including the city of Amsterdam in the Netherlands have joined the UNAIDS Fast-Track Cities initiative, committing to accelerate their HIV response and end the AIDS epidemic in cities by 2030.
Alexandra Blenkinsop   +12 more
doaj   +1 more source

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