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Identifying neurodevelopmental signatures of worry: An ultra-high field (7-Tesla) fMRI study among adolescents and young adults. [PDF]

open access: yesDev Cogn Neurosci
Objective: Worry plays an important role in anxiety disorders, but its neurodevelopment remains unclear. Worry increases during adolescence when cognitive-affective neural circuits are developing, impacting girls especially.
Westbrook C   +5 more
europepmc   +2 more sources

Amygdala volume is not associated with MRI-based markers of early cardiovascular disease. [PDF]

open access: yesInsights Imaging
Background Recent PET studies suggest a link between amygdala activity and cardiovascular disease. Altered amygdala volumes are associated with increased stressor-evoked cardiovascular reactivity, which potentially increases the risk for cardiovascular ...
Schlaeger S   +13 more
europepmc   +2 more sources

A Review of the Metabolism and Relevance to Form and Formulation of Ketamine

open access: yesEuropean Psychiatry, 2023
Introduction Ketamine is a phenylcyclohexylamine derivative comprising a racemic mixture of S- and R-ketamine that possesses anesthetic, analgesic, anti-inflammatory, and antidepressant activity.
P. Chue   +4 more
doaj   +1 more source

Effective connectivity of the amygdala during the consumption of erotic, sexual humor, and monetary rewards with a DCM-PEB approach

open access: yesPLoS ONE, 2022
While a large body of research exists on the processing of monetary rewards, less is known about sexual reward processing. This study aimed to identify effective connectivity for the consumption of sexual (erotic and sexual humor) and non-sexual ...
Yu-Chen Chan, Tai-Li Chou
doaj   +2 more sources

A 28-Day, Randomized, Controlled, Single-Blind, Phase 2 Study in Treatment-Resistant Major Depressive Disorder (TRD) Patients Receiving Intranasal Esketamine Comparing Addition of Almond Therapy TM with Treatment-as-Usual (TAU)

open access: yesEuropean Psychiatry, 2023
Introduction Treatment Resistant Depression (TRD) occurs in up to 30% of patients with Major Depressive Disorder (MDD). New treatments are clearly needed and there is a burgeoning interest in novel agents including ketamine.
P. Chue   +8 more
doaj   +1 more source

Decreased amygdala volume in adults after premature birth

open access: yesScientific Reports, 2021
Premature-born infants have impaired amygdala structure, presumably due to increased stress levels of premature birth mediated by the amygdala. However, accounting for lifelong plasticity of amygdala, it is unclear whether such structural changes persist
Benita Schmitz-Koep   +12 more
doaj   +1 more source

Vagus nerve stimulation (VNS) therapy in patients with treatment resistant depression: A systematic review and meta-analysis

open access: yesComprehensive Psychiatry, 2020
Background: Vagus nerve stimulation (VNS) therapy is approved for treatment-resistant depression (TRD). A recent 5-year comparative study prompted this review of its impact in this very severe population.
Juliana M. Bottomley   +4 more
doaj   +1 more source

Connectivity-based parcellation of the amygdala and identification of its main white matter connections

open access: yesScientific Reports, 2023
The amygdala plays a role in emotion, learning, and memory and has been implicated in behavioral disorders. Better understanding of the amygdala circuitry is crucial to develop new therapies for these disorders.
Josue M. Avecillas-Chasin   +6 more
doaj   +1 more source

Within amygdala: Basolateral parts are selectively impaired in premature-born adults

open access: yesNeuroImage: Clinical, 2021
While it is known that whole amygdala volume is lastingly reduced after premature birth, it is unknown whether different amygdala nuclei are distinctively affected by prematurity.
Benita Schmitz-Koep   +12 more
doaj   +1 more source

Abnormal Functional Connectivity of the Amygdala in Mild Cognitive Impairment Patients With Depression Symptoms Revealed by Resting-State fMRI

open access: yesFrontiers in Psychiatry, 2021
Convergent evidence indicates that individuals with symptoms of depression exhibit altered functional connectivity (FC) of the amygdala, which is a key brain region in processing emotions.
Ting Yang   +8 more
doaj   +1 more source

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