Results 91 to 100 of about 188,762 (266)

The diagnostic value of the circadian rhythm gene KLF10 in anxiety‐depressive disorders and its neuroimmune regulatory mechanisms

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu, Weifeng Guo, Jianxiang Li, Tiange Zhang, Dan Xu   +4 more
wiley   +1 more source

Multi‐voxel pattern analysis of amygdala functional connectivity at rest predicts variability in posttraumatic stress severity

Brain and Behavior, 2020
Introduction Resting state functional magnetic resonance imaging (rsfMRI) studies demonstrate that individuals with posttraumatic stress disorder (PTSD) exhibit atypical functional connectivity (FC) between the amygdala, involved in the generation of ...
Jacklynn M. Fitzgerald, Emily L. Belleau, Tara A. Miskovich, Walker S. Pedersen, Christine L. Larson   +4 more
doaj   +1 more source

Amygdala-hippocampal involvement in human aversive trace conditioning revealed through event-related functional magnetic resonance imaging [PDF]

, 1999
Previous functional neuroimaging studies have characterized brain systems mediating associative learning using classical delay conditioning paradigms.
Buchel, C, Friston, K., Armony, J., Armony, J, Dolan, R, Dolan, R. ; https://orcid.org/, Buchel, C., Friston, K   +7 more
core  

The Contribution of the Amygdala to Reward-Related Learning and Extinction

, 2017
There has been substantial research into the role of the amygdala in fear conditioning and extinction of conditioned fear. The role of the amygdala in appetitive conditioning is relatively less explored. Here, we will review research into the role of the
Corbit, Laura H., Laura Corbit, Chesworth, Rose (R18587), Rose Chesworth   +3 more
core   +1 more source

Blood Biomarkers of Alzheimer's Disease and Patterns of Structural Brain Changes in the Community

Annals of Neurology, EarlyView.
Objective We aimed to investigate the associations between Alzheimer's disease (AD)‐related blood biomarkers and changes in brain volumes and cerebrovascular burden in community‐dwelling older adults. Methods We included 361 dementia‐free participants with a Mini‐Mental State Examination (MMSE) score ≥ 27 and without prior cerebrovascular events from a
Martina Valletta, Davide Liborio Vetrano, Erika J. Laukka, Grégoria Kalpouzos, Javier Oltra, Debora Rizzuto, Marco Canevelli, Claudia Fredolini, Chengxuan Qiu, Bengt Winblad, Laura Fratiglioni, Giulia Grande   +11 more
wiley   +1 more source

Mesoscale functional connectivity of amygdala to the auditory and prefrontal cortex of macaque monkeys revealed by INS-fMRI

NeuroImage
Mammals rely heavily on their auditory system to perceive environmental threats, socially communicate, and care for the young. As an extension of the multiple sensory system including the auditory system, the amygdala evaluates the emotional salience of ...
Qianbing Li, An Ping, Yuqi Feng, Bin Xu, Baorong Zhang, Anna Wang Roe, Lixia Gao, Xinjian Li   +7 more
doaj   +1 more source

Accelerated Brain Atrophy in Epilepsy: A Prospective Population‐Based Study

Annals of Neurology, EarlyView.
Objective Previous longitudinal neuroimaging studies suggest that epilepsy is a progressive disorder. To date, these findings have relied largely on populations from tertiary centers, resulting in ascertainment bias, as severely affected individuals are more likely to be rescanned.
Marian Galovic, Rebecca S. N. Liu, Alex D. Everitt, Robert Terziev, Louis Lemieux, Matthias J. Koepp, John S. Duncan   +6 more
wiley   +1 more source

MEG evidence for dynamic amygdala modulations by gaze and facial emotions.

PLoS ONE, 2013
BackgroundAmygdala is a key brain region for face perception. While the role of amygdala in the perception of facial emotion and gaze has been extensively highlighted with fMRI, the unfolding in time of amydgala responses to emotional versus neutral ...
Thibaud Dumas, Stéphanie Dubal, Yohan Attal, Marie Chupin, Roland Jouvent, Shasha Morel, Nathalie George   +6 more
doaj   +1 more source

The influence of μ-opioid and noradrenaline reuptake inhibition in the modulation of pain responsive neurones in the central amygdala by tapentadol in rats with neuropathy [PDF]

, 2015
Treatments for neuropathic pain are either not fully effective or have problematic side effects. Combinations of drugs are often used. Tapentadol is a newer molecule that produces analgesia in various pain models through two inhibitory mechanisms, namely
Gonçalves, L, Friend, LV, Dickenson, AH
core  

A common neural system mediating two different forms of social judgement [PDF]

, 2009
Background: A wide range of neuropsychiatric conditions, including schizophrenia and autistic spectrum disorder (ASD), are associated with impairments in social function.
Santos, I. M., D. I. Donaldson, Donaldson, David, Whalley, H. C., Lawrie, Stephen M, J. W. Mckirdy, Santos, Isabel M, Donaldson, D. I., McGonigle, D. J., R. Sprengelmeyer, I. M. Santos, Hall, J., S. M. Lawrie, Sprengelmeyer, R., A. M. Mcintosh, Whalley, Heather C, Sprengelmeyer, Reiner, Johnstone, Eve C, McIntosh, Andrew M, McKirdy, J. W., J. Hall, McIntosh, A. M., A. W. Young, E. C. Johnstone, Young, A. W., H. C. Whalley, McKirdy, James W, McGonigle, David, Johnstone, E. C., Lawrie, S. M., Hall, Jeremy, D. J. Mcgonigle, Young, Andrew W   +32 more
core   +1 more source