Results 251 to 260 of about 504,545 (312)

Early Amyloid Formation and Neuroinflammatory Response in a Bigenic Mouse Model Expressing Human α-Synuclein and Aβ. [PDF]

Parkinsons Dis
Thakore R, Aldén M, Gustavsson N, Danielson L, Lins L, Sánchez JD, Arensburg AR, Paulus A, da Silva IAN, Skoryk V, Kayed R, Gouras GK, Deierborg T, Heuer A, Konings SC, Klementieva O.   +15 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Intraindividual cognitive variability predicts amyloid beta, tau PET, and dementia conversion in Down syndrome: a potential marker of cognitive resilience. [PDF]

Alzheimers Dement
Fonseca LM, Lila E, Shojaie A, Chhatwal J, Forlenza O, Beeri MS, Krinsky-McHale S, Cohen AD, Christian BT, Head E, Mapstone M, Handen B, Ances BM, Grabowski T, Chaytor NS, Zaman S, Alzheimer's Biomarkers Consortium‐ Down Syndrome (ABC‐DS) Investigators.   +16 more
europepmc   +1 more source

Transthyretin amyloid cardiomyopathy: Literature review and red‐flag symptom clusters for each cardiology specialty

ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya, Toru Kubo, Jin Endo, Seiji Takashio, Masatoshi Minamisawa, Jun Hamada, Tomonori Ishii, Hajime Abe, Hiroaki Konishi, Kenichi Tsujita   +9 more
wiley   +1 more source

Considerations for the selection and phenotyping of mouse models for the study of Alzheimer's disease. [PDF]

STAR Protoc
Boyanova S, Katsouri L, Krupic J, Hair K, Wang SH, Wiseman FK.   +5 more
europepmc   +1 more source

Amyloid PET Burden, CSF Biomarkers, and <i>APOE</i> Genotype in People With Iatrogenic and Sporadic Cerebral Amyloid Angiopathy. [PDF]

Neurology
Storti B, Capozza A, Marinoni G, Strazzabosco C, Stanziano M, Rifino N, Boncoraglio GB, Scala I, Romoli M, Paccagnella A, Canavero I, Tagliabue L, Bersano A.   +12 more
europepmc   +1 more source

Multimodal Integration of Gait Dysfunction, Amyloid PET, and Plasma Biomarkers for Differentiating Etiological Subtypes in Mild Cognitive Impairment. [PDF]

CNS Neurosci Ther
Wu J, Tang F, Lv X, Wang Y, Gao F, Shen Y, Cheng Z, Shi J.   +7 more
europepmc   +1 more source

Cortical Microinfarcts Are Related to Amyloid Pathology and Cognitive Decline in Spontaneous Intracerebral Hemorrhage. [PDF]

J Stroke
Chiang PT, Tsai HH, Lee BC, Liu CJ, Peng SJ, Lin SS, Jeng JS, Tsai LK.   +7 more
europepmc   +1 more source