Results 181 to 190 of about 85,510 (321)
Tumor necrosis factor‐alpha aggravates hippocampal damage in rat induced by amyloid beta‐peptide (25–35) [PDF]
M. Yu. Stepanichev+5 more
openalex +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang+7 more
wiley +1 more source
Circular RNA Encoded Amyloid Beta peptides-A Novel Putative Player in Alzheimer's Disease. [PDF]
Mo D+5 more
europepmc +1 more source
Beta‐amyloid peptide is toxic to cholinoceptive neurones in vivo via indirect mechanisms [PDF]
Ivan González+2 more
openalex +1 more source
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya+9 more
wiley +1 more source
On the Role of Platelet-Generated Amyloid Beta Peptides in Certain Amyloidosis Health Complications. [PDF]
Inyushin M+3 more
europepmc +1 more source
Apolipoprotein E and Alzheimer’s disease: The influence of apolipoprotein E on amyloid- and other amyloidogenic proteins [PDF]
Agosta+207 more
core +2 more sources
The 366 patients diagnosed with transthyretin amyloidosis cardiomyopathy (ATTR‐CM) were analyzed regarding their clinical characteristics in the first year after approval of tafamidis 61 mg for ATTR‐CM in Germany. Nearly two‐thirds of the patients were in an advanced disease stage and 64% met the key criteria of the “Transthyretin Amyloidosis ...
Richard J. Nies+23 more
wiley +1 more source
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi+6 more
wiley +1 more source
Biophysical characterization of longer forms of amyloid beta peptides: possible contribution to flocculent plaque formation [PDF]
Mark H. L. Lambermon+2 more
openalex +1 more source