Results 51 to 60 of about 4,929 (174)

Utilization and Prognosis of Cardiac Device Implantation in AL Versus ATTR Amyloidosis

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Introduction Cardiac amyloidosis can cause congestive heart failure, arrhythmias, and heart blocks, which frequently require cardiac device implantation (CDI). However, the differences between light chain (AL) amyloidosis and transthyretin (ATTR) amyloidosis CDI requirements are unknown. Methods A retrospective analysis was conducted using the
Bilal Hussain, Sanchit Duhan, Khawaja Hassan Akhtar, Amith Reddy Seri, Krittapoom Akrawinthawong, Janardhana Gorthi, Bijeta Keisham, Tarun Dasari   +7 more
wiley   +1 more source

Connecting the Dots in the Neuroglobin-Protein Interaction Network of an Unstressed and Ferroptotic Cell Death Neuroblastoma Model

Cells, 2019
Neuroglobin is a heme protein of which increased levels provide neuroprotection against amyloid proteinopathy and hemorrhagic damage. These cellular stressors involve the promotion of ferroptosis—an iron-dependent, lipid peroxide-accreting form of ...
Zoë P. Van Acker, Geert A. Van Raemdonck, Emilie Logie, Sara I. Van Acker, Geert Baggerman, Wim Vanden Berghe, Peter Ponsaerts, Sylvia Dewilde   +7 more
doaj   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Breast cancer and amyloid bodies: is there a role for amyloidosis in cancer-cell dormancy?

Breast Cancer: Targets and Therapy, 2017
Gerald J Mizejewski Wadsworth Center, New York State Department of Health, Albany, NY, USA Abstract: Breast cancer and Alzheimer’s disease (AD) are major causes of death in older women.
Mizejewski GJ
doaj  

Cognitive reserve against vascular contributions to cognitive impairment and dementia: A scoping review

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Vascular contributions to cognitive impairment and dementia (VCID) are common in older adults and are typically associated with cerebral small vessel disease (cSVD). However, little remains known about non‐pharmacological, modifiable lifestyle variables that may build cognitive reserve against cSVD/VCID.
Christopher E. Bauer, Colleen Pappas, Brian T. Gold   +2 more
wiley   +1 more source

Deciphering Antidiabetic, Anti‐Inflammatory, and Anti‐Cholinergic Bioactivities of Withania somnifera (L) Dunal Root Extract: An In Vitro and In Silico Investigation

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
In this investigation, Withania somnifera root ethanol extract displays anti‐inflammatory and antidiabetic properties. Though compounds including withasomniferolide B and sitoindoside IX have been previously identified as phytoconstituents in the plant, in silico analysis from this study revealed them as new lead compounds that could act as potential ...
Lufuno Mulelu, Jacqueline N. Manjia, Kolawole A. Olofinsan, Londiwe Xulu, Motlalepula G. Matsabisa   +4 more
wiley   +1 more source

Immunoglobulin Light Chain Amyloidosis

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Waxy, purple nodules and plaques distributed across the distal fingers and thenar eminences. ABSTRACT Symmetric, purpuric hand nodules and macroglossia prompted skin biopsy revealing immunoglobulin light chain amyloidosis, leading to the diagnosis of multiple myeloma.
Justin Lyon, Ashley Khouri, Katheryn A. Bell, Jamie Zussman   +3 more
wiley   +1 more source

Diagnostic pathway for cardiac amyloidosis from the healthcare professional’s perspective: results from the French DIAM-ATTR survey

Annals of Medicine
Background Diagnosis of cardiac amyloidosis (CA) is complex and implicates several medical specialists. CA is usually suspected based on symptoms (‘red flags’) and non-invasive imagery.
Silvia Oghina, Damien Legallois, Fabien Hyafil, Walid Amara, Emmanuel Andrès, Thomas Bardin, Pauline Fournier, Sandra Guignard, Céline Labeyrie, Nicolas Piriou, Olivier Toulza, Romain Tresorier, Giorgia Canali, Margaux Dubois, Benoit Bouquillon, Cédric Sauvage, Pierre Sabouret, Philippe Charron, Thibaud Damy   +18 more
doaj   +1 more source

Familial Amyloid Polyneuropathy Type IV (FINNISH) with Rapid Clinical Progression in an Iranian Woman: A Case Report

Iranian Journal of Medical Sciences, 2016
Familial amyloid polyneuropathy (FAP) type IV (FINNISH) is a rare clinical entity with challenging neuropathy and cosmetic deficits. Amyloidosis can affect peripheral sensory, motor, or autonomic nerves.
Arash Babaei-Ghazani, Bina Eftekharsadat   +1 more
doaj  

Ageing‐Associated Dysregulation of Myogenic Differentiation in Inclusion Body Myositis

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Skeletal muscle is a postmitotic tissue dependent on a complex and tightly regulated regeneration process involving numerous intracellular and extracellular factors, including myogenic regulatory factors (MRFs), cytokines and myokines. Quiescent satellite cells are activated by physiological stimuli, injury or other traumatic insults for the ...
Geert M. de Vries, Willem De Ridder, Jonathan Baets   +2 more
wiley   +1 more source