Results 181 to 190 of about 36,206 (272)

Divalent cation tolerance protein binds to β-secretase and inhibits the processing of amyloid precursor protein.

, 2013
Runzhong Liu, Haibo Hou, Xuelian Yi, Shanwen Wu, Huan Zeng   +4 more
openalex   +2 more sources

A Helix-to-Coil Transition in the Transmembrane Dimer of the Amyloid Precursor Protein is Required for Proteolysis by γ-Secretase [PDF]

, 2009
Tzu-Chun Tang, Takeshi Sato, Pascal Kienlen‐Campard, Stefan N. Constantinescu, Jean‐Noël Octave, Steven O. Smith   +5 more
openalex   +1 more source

Alzheimer's Disease: From Pathogenesis to Emerging Therapeutic Targets. [PDF]

J Clin Med
Takahashi T, Muguruma K.
europepmc   +1 more source

Investigations of γ-secretase substrates Amyloid precursor protein and p75 neurotrophin receptor in zebrafish

, 2019
Tanya Jayne
openalex   +1 more source

APP E590D mutation increases generation of Aβ and Aη peptides and exacerbates tauopathy. [PDF]

NPJ Dement
Liu T, Wetzel L, Roy D, Zhang K, Zhu Z, Kumaraguru P, Gorthi V, Jeon H, Woo JA, Kang DE.   +9 more
europepmc   +1 more source

Retinoic Acid-Elicited RARα/RXRα Signaling Attenuates Aβ Production by Directly Inhibiting γ-Secretase-Mediated Cleavage of Amyloid Precursor Protein

, 2013
Arun Kapoor, Bo‐Jeng Wang, Wen‐Ming Hsu, Ming‐Yun Chang, Shu‐Mei Liang, Yung-Feng Liao   +5 more
openalex   +2 more sources

Fluoxetine Repurposing Mitigates Alzheimer's Disease Pathology via the GSK3β-CREB-ADAM10 Axis. [PDF]

Int J Mol Sci
Lee SH, Son Y, Jang H, Kim HY, Kim KS, Lee HS, Lee HJ.   +6 more
europepmc   +1 more source

Astrocytes regulate α-secretase-cleaved soluble amyloid precursor protein secretion in neuronal cells: Involvement of group IIA secretory phospholipase A2

, 2015
Xiaoguang Yang, W. Sheng, Devin M. Ridgley, Mark A. Haidekker, Grace Y. Sun, J.C. Lee   +5 more
openalex   +2 more sources

Double-edged role of N6-methyladenosine reader YTH structural domain family protein 2 in neurological disorders: Molecular mechanisms and translational prospects. [PDF]

World J Exp Med
Liu YM, Liu M, Yuan H, Li B.
europepmc   +1 more source

Caspase-8, association with Alzheimer\u27s disease and functional analysis of rare variants [PDF]

, 2017
Cruchaga, Carlos, et al.,, Lord, Jenny
core   +1 more source