Results 81 to 90 of about 116,695 (256)

Role of Anabolic Anti-Osteoporosis Therapy in Diabetes Subjects

Indian Journal of Endocrinology and Metabolism
Diabetes mellitus (DM) is a metabolic disorder that leads to the destruction of various tissues including bones. The pathogenesis of osteoporosis (OP) varies in DM due to many specific factors.
Harsh Durgia, Rajan Palui, Jayaprakash Sahoo, Sadishkumar Kamalanathan, Dukhabandhu Naik   +4 more
doaj   +1 more source

Overcoming resistance to anabolic SARM therapy in experimental cancer cachexia with an HDAC inhibitor

EMBO Molecular Medicine, 2020
No approved therapy exists for cancer‐associated cachexia. The colon‐26 mouse model of cancer cachexia mimics recent late‐stage clinical failures of anabolic anti‐cachexia therapy and was unresponsive to anabolic doses of diverse androgens, including the
Sophia G Liva, Yu‐Chou Tseng, Anees M Dauki, Michael G Sovic, Trang Vu, Sally E Henderson, Yi‐Chiu Kuo, Jason A Benedict, Xiaoli Zhang, Bryan C Remaily, Samuel K Kulp, Moray Campbell, Tanios Bekaii‐Saab, Mitchell A Phelps, Ching‐Shih Chen, Christopher C Coss   +15 more
doaj   +1 more source

Anabolic steroids: use vs. misuse [PDF]

, 2009
Anabolic steroids: use vs. misuse The diploma thesis is aimed at topic of anabolic steroids misuse. It is trying to create complex critical review about this topic.
Žofková, Kristina
core  

Anabolic steroids for treating pressure ulcers

, 2014
This is the protocol for a review and there is no abstract. The objectives are as follows: To determine the effects of anabolic steroids on the healing of pressure ulcers of any grade, in any care setting; to establish whether anabolic steroids are an ...
Naing, Cho, Cho Naing, Racloz, Vanessa, Whittaker, Maxine A., Aung, Kyan, Maxine A Whittaker, Vanessa Racloz, Kyan Aung   +7 more
core   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Anabolic steroids, acute myocardial infarction and polycythemia: A case report and review of the literature

, 2008
Kathleen Stergiopoulos1, Joseph J Brennan2, Robin Mathews1, John F Setaro2, Smadar Kort11Division of Cardiovascular Medicine, Department of Internal Medicine, Stony Brook University Medical Center, Stony Brook, NY, USA; 2Division of Cardiovascular ...
Robin Mathews, Smadar Kort, John F Setaro, Joseph J Brennan, Kathleen Stergiopoulos   +4 more
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Anabolic Steroid Abuse: Federal Efforts to Prevent and Reduce Anabolic Steroid Abuse among Teenagers [PDF]

, 2007
A letter report issued by the Government Accountability Office with an abstract that begins "The abuse of anabolic steroids by teenagers--that is, their use without a prescription--is a health concern. Anabolic steroids are synthetic forms of the hormone
United States. Government Accountability Office.
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Ribonucleotides Amplify Mitochondrial DNA‐Driven cGAS–STING Activation via FdUMP‐ribonucleotide Hybrid Particles to Potentiate Chemoimmunotherapy

Advanced Science, EarlyView.
This work develops a metabolic sharing strategy that employs cytidine monophosphate (CMP) to competitively reprogram floxuridine (FUDR) pyrimidine metabolism in colorectal tumor cells. Elevated intracellular FdUMP induces nucleotide imbalance, drives mitochondrial DNA release and cGAS‐STING innate immune cascade activation, and potentiates robust ...
Chao Wang, Chenxuan Zhao, Yesong Yao, Zhiwen Zou, Anxin Shi, Zhuo Feng, Mingkang Yang, Yue Yu, Yang Liu, Xuehui Rui, Jinhui Wu   +10 more
wiley   +1 more source

Unraveling Anabolic Resistance in Sarcopenia: A Narrative Synthesis of Age-Related Impairments in Muscle Protein Synthesis [PDF]

The Asian Journal of Kinesiology
OBJECTIVES Anabolic resistance, characterized by the diminished muscle protein synthesis (MPS) response to anabolic stimuli, represents the fundamental pathophysiological mechanism underlying age-related sarcopenia.
Hyun Joo Kang
doaj   +1 more source

Emerging anabolic treatments in osteoporosis

, 2011
Anabolic treatment that remodels bone tissue and restores bone biomechanical competence is essential in the treatment of osteoporosis. In addition, long term antiresorptive therapy may have limitations because of the reduced renewal of bone tissue.
Mosekilde, L, Rejnmark, L, Tørring, O
core   +1 more source