Results 101 to 110 of about 57,256 (260)

Comprehensive Evaluation of Treatment Patterns in Postmenopausal Patients with Osteoporosis without Fractures: Insights from Tertiary Care Institutions and Nationwide OMOP-CDM Data [PDF]

open access: yesEndocrinology and Metabolism
Background Osteoporosis is a global health concern. Despite emerging treatment options for this condition, limited data are available on hospital practices in South Korea.
Kyoung Jin Kim   +9 more
doaj   +1 more source

Plant‐derived extracellular vesicle‐like particles as novel osteoanabolic agents: Activating bone morphogenetic protein 2/Smads signaling axis for bone regeneration in postmenopausal osteoporosis

open access: yesInterdisciplinary Medicine, EarlyView.
Illustration depicting the isolation of Dipsaci Radix derived extracellular vesicle‐like particles and their function in alleviating osteoporosis. (A) Extraction and characterization detection process of extracellular vesicle‐like particles derived from Dipsaci Radix roots. (B) Cell experiments in vitro, Dipsaci Radix derived extracellular vesicle‐like
Qing Zhao   +12 more
wiley   +1 more source

Gene Expression in Hair Follicle Dermal Papilla Cells after Treatment with Stanozolol

open access: yesBiomarker Insights, 2009
Doping with anabolic agents is a topic in sports where strength is crucial, e.g. sprinting, weight lifting and many more. Testosterone and its functional analogs are the drugs of choice taken as pills, creams, tape or injections to increase muscle mass ...
M. Reiter   +3 more
doaj  

Evaluation of anatomical and histopathological changes in target organs of cattle slaughtered in Sardinia as a result of the illegal use of growth hormones. Preliminary results [PDF]

open access: yes, 2008
Within the bovine specie, illegal use of anabolic agents can be grouped into four categories: beta-agonists, thyrostatics, glucocorticoids, sexual steroids.
Anfossi, Antonio   +6 more
core  

Characteristics of drug and dietary supplement inquiries by college athletes. [PDF]

open access: yes, 2010
BackgroundIn the United States, the National Center for Drug Free Sport manages the drug-testing programs for athletes of the National Collegiate Athletic Association (NCAA).
Ambrose, Peter J   +3 more
core   +1 more source

Holistic bone developing microenvironment engineered apoptotic extracellular vesicles recapitulate multidimensional developmental signatures in adult and senile bone repair

open access: yesInterdisciplinary Medicine, EarlyView.
The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu   +11 more
wiley   +1 more source

The Problem of Doping [PDF]

open access: yes, 2008
In this Essay, we examine Professor Michael J. Sandel and Judge Richard A. Posner\u27s thoughts on how to draw the line between substances and techniques that are fair game and those that constitute doping; whether there is a difference between sport and
Coleman, Doriane Lambelet   +1 more
core   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

open access: yesInterdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu   +6 more
wiley   +1 more source

The Effect of Temperature on Trophic Discrimination of Stable Isotopes (13C and 15N) and Biokinetics in Common Carp (Cyprinus carpio, L. 1758)

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Stable isotope analysis (SIA) provides essential information toward a better understanding of trophic ecology. However, the interpretation of SIA results relies on assumptions about the trophic discrimination factor (TDF), which aims to improve the accuracy but may lead to bias.
I. Kuklina   +6 more
wiley   +1 more source

Effects of testosterone and high‐dose anabolic steroids on orthodontic‐induced bone remodeling and root resorption: An animal study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis   +11 more
wiley   +1 more source

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