Results 211 to 220 of about 29,830 (263)
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Emerging anabolic agents in the treatment of osteoporosis
Expert Opinion on Emerging Drugs, 2017Osteoporosis is a common skeletal disease with serious consequences due to osteoporotic fractures and high costs to society for post-fracture care. Most patients at high risk for fracture are not receiving care to reduce fracture risk. The osteoporosis treatment gap has reached crisis proportions.
Christina, Lovato, E Michael, Lewiecki
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2003
The idea that secretions of the testis might regulate body composition is as old as humanity itself. Humans have known since antiquity that “...you can take away the vigor of men by removing their testes.” Many cannibal tribes practiced castration on their victims several weeks prior to the sacrificial ritual.
Shalender Bhasin +2 more
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The idea that secretions of the testis might regulate body composition is as old as humanity itself. Humans have known since antiquity that “...you can take away the vigor of men by removing their testes.” Many cannibal tribes practiced castration on their victims several weeks prior to the sacrificial ritual.
Shalender Bhasin +2 more
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An enzyme immunoassay for the anabolic agent zeranol
Food Additives and Contaminants, 1989A competitive enzyme immunoassay (EIA) for the detection and quantitation of zeranol has been developed. The assay involves the use of excess second antibody adsorbed onto the walls of a microtitration plate well. Enzyme-labelled zeranol, prepared by the N-succinimidyl ester method, and standard or samples are added to the wells followed by zeranol ...
P J, Patel, S N, Dixon
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Anabolic Agents for Osteoporosis
Treatments in Endocrinology, 2006Antiresorptive agents for osteoporosis are a cornerstone of therapy, but anabolic drugs have recently widened our therapeutic options. By directly stimulating bone formation, anabolic agents reduce fracture incidence by improving other bone qualities in addition to increasing bone mass. Teriparatide (human parathyroid hormone[1-34]) has clearly emerged
Monica, Girotra +2 more
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Anabolic Agents for Osteoporosis
Abstract The international VERO Trial addressed (1) whether teriparatide offers better fracture protection than risedronate, (2) which patients benefit from this treatment, and (3) the time pattern of the FRAX-defined major osteoporotic fracture (MOF) efficacy.openaire +1 more source
The Absorption, Distribution and Excretion of Anabolic Agents
Journal of Animal Science, 1983The metabolic fate of the anabolic agents, diethylstilbestrol, hexestrol, trenbolone acetate, zeranol and the endogenous steroids are discussed under the headings absorption, distribution and excretion. There is an optimum concentration of anabolic agent in the systemic circulation that results in a maximum increase in growth rate of farm animals. This
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Anabolic agents for treating postmenopausal osteoporosis
Joint Bone Spine, 2001The main efficacy criterion for drugs against osteoporosis is protection against fractures. Many resorption-inhibiting agents meet this criterion, including estrogens, alendronate, risedronate, raloxifene, calcitonin, and calcium-vitamin D supplements).
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2003
Bone remodeling is a complex but coupled process in which old bone is resorbed, followed by the formation of new bone. Ten percent of the human skeleton is remodeled per year. Osteoporosis is a disorder of bone remodeling characterized by uncoupling of resorption from formation. The net result is a loss of bone mass.
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Bone remodeling is a complex but coupled process in which old bone is resorbed, followed by the formation of new bone. Ten percent of the human skeleton is remodeled per year. Osteoporosis is a disorder of bone remodeling characterized by uncoupling of resorption from formation. The net result is a loss of bone mass.
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Latest on Anabolic Agents for Osteoporosis Treatment
Endocrinology and Metabolism Clinics of North AmericaIn the last decades, novel therapeutics with anabolic bone properties have been developed and are currently used in the management of osteoporosis particularly in patients with high-risk of fragility fractures. These drugs include PTH-Related Analogues, teriparatide and abaloparatide, and the anti-sclerostin agent romosozumab, this latter drug ...
di Filippo L., Rosen C. J.
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Methandrostenolone, an Oral Anabolic Agent
Southern Medical Journal, 1964E C, JUNGCK, R B, GREENBLATT
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