Results 61 to 70 of about 29,623 (261)

Use of androgenic anabolic steroids by patients under treatment for substance use disorder: case series

open access: yesJornal Brasileiro de Psiquiatria
The present study reports several case studies about the use of androgenic-anabolic steroids (AAS) by patients under treatment for substance use disorder (SUD).
Julio Mario Xerfan do Amaral   +1 more
doaj   +1 more source

Sclerostin

open access: yesJournal of Osteoporosis, 2010
The striking clinical benefits of intermittent parathyroid hormone in osteoporosis have begun a new era of skeletal anabolic agents. One potential new agent is monoclonal antibody to sclerostin, a potent inhibitor of osteoblastogenesis.
Stuart L. Silverman
doaj   +1 more source

Validation of screening method for determination of methyltestosterone in fish [PDF]

open access: yesMacedonian Veterinary Review, 2013
Anabolic androgenic steroids are synthetic derivatives of testosterone, which is the primary male sex hormone. These anabolic agents are used to increase the weight gain, to improve the food efficiency, storing proteins and to decrease fatness.
Stojkovski Velimir   +5 more
doaj  

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla   +13 more
wiley   +1 more source

Effects of anabolic steroid treatment associated with physical training in adipose tissue of male Wistar rats

open access: yesActa Scientiarum. Health Sciences, 2015
Anabolic androgenic-steroids (AAS) include a broad class of synthetic derivatives of testosterone, being nandrolone decanoate the most widely used in sports environment.
Marcela de Paiva Foletto   +5 more
doaj   +1 more source

Online information and availability of three doping substances (anabolic agents) in sports: role of pharmacies. [PDF]

open access: yesFront Pharmacol, 2023
Garcia JF   +10 more
europepmc   +1 more source

PEPITEM Regulates the Synovial Microenvironment During Immune‐Mediated Inflammatory Arthritis to Limit Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Here we investigate the status of the adiponectin–PEPITEM pathway in early, treatment naive rheumatoid arthritis (RA) and psoriatic arthritis (PsA) and the therapeutic efficacy of PEPITEM administration in preclinical models. Methods Peripheral blood was isolated from patients with clinical suspect arthralgia and suspected inflammatory ...
Mussarat Wahid   +34 more
wiley   +1 more source

Effectiveness of anabolic and anti-resorptive agents for preventing postmenopausal osteoporosis fractures: a systematic review and network meta-analysis

open access: yesJournal of Orthopaedic Surgery and Research
Background While anabolic agents are highly effective in stimulating bone formation, their benefits are transient and tend to plateau after prolonged use. This necessitates a transition to anti-resorptive therapies. We aimed to estimate anti-osteoporosis
Peng Su   +3 more
doaj   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel   +12 more
wiley   +1 more source

Spray‐Dried Engineered Escherichia coli Whole‐Cell Biocatalysts Enable Cell Recycling and In Vivo α‐Ketoglutarate and NADPH Regeneration for Efficient Codeine Manufacture

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT A recombinant whole‐cell biocatalytic approach provides several advantages over isolated enzymes, such as improved enzyme stability, in vivo cofactor regeneration, and the facilitation of cascade reactions within a single cell. Whole‐cell biocatalysis has gained attention in medicinal opioid production, due to its technical and economic ...
Ali Jahanian   +4 more
wiley   +1 more source

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