Results 51 to 60 of about 42,152 (299)

Long‐term impact of Elexacaftor/Tezacaftor/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: A real‐world cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta, Luigi Angelo Fiorito, Roberta Vescovo, Anna Virgilio, Giulia Amato, Giuseppe Cimino   +5 more
wiley   +1 more source

Anabolic steroids as object of regulation in criminal law

Zbornik Radova Pravnog Fakulteta u Splitu, 2010
For many years athletes have used anabolic steroids, but today unaware of the risks associated with anabolic steroids use, there are more and more non-athletes, even adolescents that are ingesting steroids at an alarming rate.
Matko Pajčić, Lucija Sokanović
doaj  

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Further Insights Into the Metabolism of LGD‐4033 in Human Urine. Part 1. Structure Elucidation of Additional Important Metabolites

Drug Testing and Analysis, EarlyView.
Well‐characterized, chemically synthesized molecules related to LGD‐4033 metabolism were used as analytical standards for the analysis of LGD‐4033 post‐administration urine samples. This approach offered further insights into LGD‐4033 metabolism, providing solid experimental proof for the structure of important previously reported metabolites and ...
Yiannis S. Angelis, Panagiotis Sakellariou, Mario Thevis, Andreas Thomas, Michael Petrou, Emmanuel N. Pitsinos   +5 more
wiley   +1 more source

Investigations Into the Human Metabolism of Trestolone (7α‐Methyl‐19‐Nortestosterone)

Drug Testing and Analysis, EarlyView.
As the known metabolites of 7α‐methyl‐19‐nortestosterone (MENT), M1 and M2, suffer from chromatographic issues under routine doping control conditions, the human metabolism of MENT was reinvestigated. From the numerous new metabolites detected, especially, M5 and M10 were identified as the most promising candidates to be implemented into routine ...
Thomas Piper, Gregor Fusshöller, Mario Thevis   +2 more
wiley   +1 more source

Vitamin C Prevents Hypogonadal Bone Loss [PDF]

, 2012
Epidemiologic studies correlate low vitamin C intake with bone loss. The genetic deletion of enzymes involved in de novo vitamin C synthesis in mice, likewise, causes severe osteoporosis. However, very few studies have evaluated a protective role of this
Brenda Smith, Harry C. Blair, Jameel Iqbal, Jay Cao, Jeffrey I. Mechanick, Jianhua Li, Lida Guo, Ling-Ling Zhu, Liu Peng, Merry Sun, Mone Zaidi, Raymond Zhou, Surinder S. Moonga, Tony Yuen, Yuanzhen Peng, Zhuan Bian   +15 more
core   +6 more sources

Anabolic androgenic steroids and cardiomyopathy: an update

Frontiers in Cardiovascular Medicine, 2023
Anabolic androgenic steroids (AAS) include endogenously produced androgens like testosterone and their synthetic derivatives. Their influence on multiple metabolic pathways across organ systems results in an extensive side effect profile.
Kahtan Fadah, Gokul Gopi, Ajay Lingireddy, Vanessa Blumer, Tracy Dewald, Robert J. Mentz   +5 more
doaj   +1 more source

Body Image Perception: Adolescent Boys and Avatar Depiction in Video Games [PDF]

, 2016
Research on mass media’s impact on body image has mostly been focused on females thus far. Of the little research that has been done on male body image, most of it has been focused on adult males, and therefore the effect of mass media on adolescent boys’
Raman, Usha
core   +1 more source

Teacher‐Led Universal Eating Disorder Prevention Programmes in Schools: A Scoping Review

European Eating Disorders Review, EarlyView.
ABSTRACT Objective This scoping review seeks to evaluate the efficacy of teacher‐led interventions in mitigating risk factors related to eating disorders, considering the necessity for universal prevention programmes that can be effectively administered by educators.
Jessica Parker, Lauren Makin, Karina Allen, Kate Tchanturia   +3 more
wiley   +1 more source

Investigation of the content of anabolic steroids in food supplements used in sports practice

All Life, 2023
The goal of this study is to establish the presence or absence of anabolic androgenic steroids in food supplements implemented in sports practice, to assess the health risk from intake of food supplements with quality and content discrepancies in ...
Elina Petkova-Gueorguieva, Stanislav Gueorguiev, Hristina Lebanova, Anna Mihaylova, Vasil Madzharov   +4 more
doaj   +1 more source