A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs [PDF]
Chikungunya virus (CHIKV) is a globally spreading alphavirus against which there is no commercially available vaccine or therapy. Here we use a genome-wide siRNA screen to identify 156 proviral and 41 antiviral host factors affecting CHIKV replication ...
Berre, Stefano +16 more
core +5 more sources
The overall objective of this study was to determine the dose response to four levels of cashew nut shell extract in a granulated form (CNSE, containing 59% anacardic acid and 18% cardol) on culture pH, rumen fermentation metabolites, and apparent ...
Chandler Compton +6 more
doaj +1 more source
Regulation of transcription by the Arabidopsis UVR8 photoreceptor involves a specific histone modification [PDF]
The photoreceptor UV RESISTANCE LOCUS 8 (UVR8) specifically mediates photomorphogenic responses to UV-B wavelengths. UVR8 acts by regulating transcription of a set of genes, but the underlying mechanisms are unknown. Previous research indicated that UVR8
Herzyk, Pawel +2 more
core +1 more source
Nejire/dCBP-mediated control of H3 acetylation and transcriptional regulation by testis-specific Plus3 domain proteins during Drosophila spermatogenesis [PDF]
Spermatogenesis describes the development from germ line stem cells to highly specialized sperm. Drosophila melanogaster spermatogenesis is a good model system for chromatin remodelling processes as many of these processes are similar in mammals and in ...
Hundertmark, Tim
core +1 more source
Hypertension represents one of the most common maladies of western civilizations caused by bad dietary practices and lack of exercise. Angiotensin-I-converting enzyme inhibitors (ACEi) have been shown to be very efficient in the prevention of ...
Maria Teresa Salles Trevisan +5 more
doaj +1 more source
Calcium anacardate as growth promoter for piglets at the nursery phase [PDF]
: The objective of this work was to evaluate the effects of the dietary inclusion of calcium anacardate on the performance, diarrhea incidence, blood parameters, intestinal morphometry, and pH of gastrointestinal contents in piglets from 21 to 42 days of
Amanda Veruska Silva de Matos +7 more
doaj +1 more source
Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy. [PDF]
Aging is characterized by the progressive loss of physiological function in all organisms. Remarkably, the aging process can be modulated by environmental modifications, including diet and small molecules.
Andersen, Julie +8 more
core +1 more source
Influence of leaf trichome type, and density on the host plant selection by the greenhouse whitefly, Trialeurodes vaporariorum (Hemiptera: Aleyrodidae) [PDF]
Host selection by adult greenhouse whitefly Trialeurodes vaporariorum (Westwood) was assessed on two pelargonium plant cultivars, Pelargonium x domesticum (regal) and P. x hortorum (zonal) using Petri dish bioassay chambers in choice and no-choice tests.
AH Medeiros +46 more
core +1 more source
Two New Alkylanacardic Acids, Ozorcardic A and B, from
Two new alkylanacardic acids, ozorcardic A ( 1 ) and B ( 2 ), along with the known and related metabolite anacardic acid ( 3 ), were isolated from Ozoroa pulcherrima.
Tsague Dongmo Christelle +5 more
doaj +1 more source
Synthesis of Biscardanol as Key Intermediary in Preparation of Bistioxanthones
The cashew nut shell liquid (CNSL) is an important source of phenolic compounds such as anacardic acids, cardols and cardanols. These compounds present many biological activities. The components of CNSL were isolated and purified by column chromatography.
Glaucia Almeida Nunes +3 more
doaj +1 more source

