Results 71 to 80 of about 273,502 (301)

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

Advanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang, Zhaxi Zerang, Linjin You, Ziye Liu, Rong Nie, Fuwei Qi, Fenfen Gao, Chengmu Zhao, Wantong Ma, Jinghan He, Xiaoru Wang, Shanquan Wu, Bo Liu, Xinyao Liu, Dongsheng Lei, Dejuan Zhi, Dongsheng Wang   +16 more
wiley   +1 more source

Effectiveness of progressive core stabilization training on anaerobic performance in elite athletes: a randomized controlled trial

BMC Sports Science, Medicine and Rehabilitation
Background Although progressive core stabilization training (PCST) improves sport-specific abilities, the effects of PCST on anaerobic performance and fatigue are still unclear today.
Gülşah Başandaç, Gülşah Barğı, Volga Bayrakcı Tunay   +2 more
doaj   +1 more source

Assessment and Differences in Anaerobic Capacity of Football Players Playing on Different Positions in the Team, Using Rast Test [PDF]

Sport Mont, 2016
Today's rapid development of football in all stages allocates a dominant role to conditional training. Players who participated in the study played in the 4:4:2 formation, therefore the classification has been made according to the playing position in ...
Slobodan Andrašić, Milan Cvetković, Zoran Milić, Darijan Ujsasi, Dejan Orlić   +4 more
doaj  

The Influence of Body Size and Hemoglobin Multiplicity on Critical Oxygen Threshold in Red Drum (Sciaenops ocellatus) [PDF]

, 2016
Hypoxia is common in marine environments and fishes use a suite of cardiorespiratory adjustments to defend aerobic metabolism, including reducing standard metabolic rate (SMR), the minimum metabolic rate needed to sustain life at a specified temperature,
Pan, Yihang
core   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

The Effect of Wearing a Lower Body Compression Garment on Anaerobic Exercise Performance in Division I NCAA Basketball Players

Sports, 2019
Lower body compression (LBC) has been shown as an effective recovery tool from basketball but it is unknown how it affects performance. The purpose of this study was to examine the effects of wearing a LBC garment on anaerobic exercise performance in ...
Christopher Ballmann, Hunter Hotchkiss, Mallory Marshall, Rebecca Rogers   +3 more
doaj   +1 more source

Stabilization of Single Metal Atoms on Graphitic Carbon Nitride: Synthetic Strategies and Emerging Applications

Advanced Science, EarlyView.
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang, Junjie Cui, Zhenjie Yao, Boyuan Zhu, Nithinraj Panangattu Dharmarajan, Ajayan Vinu, Junwu Zhu   +6 more
wiley   +1 more source

Anaerobic capacity, isometric endurance, and Laser sailing performance

Journal of Sports Sciences, 2007
Laser sailors have to tolerate fatiguing contractions of the lower-body muscles for prolonged periods. The aims of the present study were (1) to evaluate the difference between top-ranked and club sailors, in their capacity to resist fatigue during sustained isometric and maximal power exercise, and (2) to examine the relationships between the above ...
Vangelakoudi, A., Vogiatzis, I., Geladas, N.   +2 more
openaire   +3 more sources

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Rapid Metabolic Recovery Following Vigorous Exercise in Burrow-Dwelling Larval Sea Lampreys (\u3cem\u3ePetromyzon marinus\u3c/em\u3e) [PDF]

, 2001
Although the majority of the sea lamprey’s (Petromyzon marinus) life cycle is spent as a burrow-dwelling larva, or ammocoete, surprisingly little is known about intermediary metabolism in this stage of the lamprey’s life history.
Bradshaw, Philip G., Claude, Jaime F., Joanis, Vincent, Swindell, Shannon L., Wilkie, Michael P.   +4 more
core   +1 more source