Results 71 to 80 of about 61,025 (337)

Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun   +10 more
wiley   +1 more source

Impact of Salmonella genome rearrangement on gene expression

open access: yesEvolution Letters, Volume 6, Issue 6, Page 426-437, December 2022., 2022
Abstract In addition to nucleotide variation, many bacteria also undergo changes at a much larger scale via rearrangement of their genome structure (GS) around long repeat sequences. These rearrangements result in genome fragments shifting position and/or orientation in the genome without necessarily affecting the underlying nucleotide sequence.
Emma V. Waters   +4 more
wiley   +1 more source

Effect of Volatile Fatty Acid Concentration on Anaerobic Degradation Rate from Field Anaerobic Digestion Facilities Treating Food Waste Leachate in South Korea

open access: yesJournal of Chemistry, 2015
The purpose of this study was to investigate the effect of volatile fatty acid concentration on anaerobic degradation rate of food waste leachate in the anaerobic digestion facilities. The anaerobic digestion facilities treating food waste leachate (FWL),
Dong-Jin Lee   +9 more
doaj   +1 more source

Effect of turbulent diffusion in modeling anaerobic digestion [PDF]

open access: yes
In this study, the impact of turbulent diffusion on mixing of biochemical reaction models is explored by implementing and validating different models. An original codebase called CHAD (Coupled Hydrodynamics and Anaerobic Digestion) is extended to incorporate turbulent diffusion and validate it against results from OpenFOAM with 2D Rayleigh-Taylor ...
arxiv   +1 more source

uGLAD: Sparse graph recovery by optimizing deep unrolled networks [PDF]

open access: yesarXiv, 2022
Probabilistic Graphical Models (PGMs) are generative models of complex systems. They rely on conditional independence assumptions between variables to learn sparse representations which can be visualized in a form of a graph. Such models are used for domain exploration and structure discovery in poorly understood domains.
arxiv  

Modulating Iron Crystals with Lattice Chalcophile‐Siderophile Elements for Selective Dechlorinations Over Hydrogen Evolution

open access: yesAdvanced Science, EarlyView.
Lattice engineering of nFe0 crystals with chalcophile‐siderophile elements optimizes the iron microenvironment, enhancing hydrophobicity, electron transfer, and selective dechlorination efficiency while reducing hydrogen evolution reaction (HER). The Cu─S─nFe0 material shows a 20‐fold increase in dechlorination rate, a 150‐fold decrease in HER, and ...
Xiaohong Hu   +10 more
wiley   +1 more source

Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics

open access: yesAdvanced Science, EarlyView.
Intestinal barrier stability is vital for gut health. Plastic polyethylene terephthalate (PET) disrupts this barrier, causing inflammation and infections. This study encodes transforming growth factor‐β into EcN and modifies its surface with pH‐responsive polymer (EcNT@L), creating an oral drug delivery system to repair nano PET‐induced intestinal ...
Wenxin Chen   +9 more
wiley   +1 more source

A Sequential Release Micro‐nano System for Colitis Therapy via Gut Microbiota and Immune Regulation

open access: yesAngewandte Chemie, EarlyView.
The micro‐nano system achieves the sequential release of drugs in response to gut microbiota and reactive oxygen species (ROS). Inulin prebiotics restore gut microbiota balance. Selenium compounds scavenge ROS and promote macrophage polarization, while 3‐oxolithocholic acid suppresses TH17‐cell differentiation. As a multifactorial therapeutic approach,
Dongdong Zhu   +9 more
wiley   +2 more sources

The Encapsulation Strategies for Targeted Delivery of Probiotics in Preventing and Treating Colorectal Cancer: A Review

open access: yesAdvanced Science, EarlyView.
This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong   +5 more
wiley   +1 more source

Anaerobic digestion of aliphatic polyesters

open access: yesWater Science and Technology, 2016
Anaerobic processes for the treatment of plastic materials waste represent versatile and effective approach in environmental protection and solid waste management. In this work, anaerobic biodegradability of model aliphatic polyesters, poly(L-lactic acid) (PLA), and poly(ɛ-caprolactone) (PCL), in the form of powder and melt-pressed films with varying ...
Veronika Kužníková   +3 more
openaire   +3 more sources

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